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不同肥胖症手术对代谢综合征患者的疗效分析

Analysis of the Efficacy of Different Obesity Surgeries in Patients with Metabolic Syndrome.

作者信息

Qi Tengfei, Ding Yunfa, Dai Xiaojiang, He Jipei, Zhang Hongbin, Wu Liangping

机构信息

Jinshazhou Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.

Guangzhou University of Chinese Medicine, Guangzhou, China.

出版信息

Obes Surg. 2025 Mar;35(3):763-774. doi: 10.1007/s11695-025-07673-3. Epub 2025 Jan 11.

Abstract

BACKGROUND

To investigate the effectiveness of different bariatric metabolic surgeries in improving metabolic syndrome indicators in patients.

METHODS

A retrospective analysis was conducted on obese patients who underwent laparoscopic sleeve gastrectomy (LSG), laparoscopic sleeve gastrectomy + jejunojejunal bypass (LSG + JJB), and laparoscopic Roux-en-Y gastric bypass (LRYGB). Patients were categorized into groups based on their surgical procedure: LSG (N = 199), LSG + JJB (N = 242), and LRYGB (N = 288).

RESULTS

Successful laparoscopic bariatric metabolic surgery was achieved in 729 patients. Indicators related to body mass, glucose metabolism, insulin resistance, lipid metabolism, and kidney function showed significant improvement compared to the preoperative period.

CONCLUSIONS

LSG, LSG + JJB, and LRYGB all demonstrate significant effectiveness in promoting weight loss and improving glycolipid metabolism in the short term. Post-surgery, symptoms of metabolic syndrome improved compared to the preoperative period, with LRYGB showing superior effectiveness over LSG + JJB and LSG.

摘要

背景

探讨不同减重代谢手术对改善患者代谢综合征指标的有效性。

方法

对接受腹腔镜袖状胃切除术(LSG)、腹腔镜袖状胃切除术+空肠空肠旁路术(LSG+JJB)和腹腔镜Roux-en-Y胃旁路术(LRYGB)的肥胖患者进行回顾性分析。根据手术方式将患者分为三组:LSG组(N=199)、LSG+JJB组(N=242)和LRYGB组(N=288)。

结果

729例患者成功实施了腹腔镜减重代谢手术。与术前相比,体重、糖代谢、胰岛素抵抗、脂代谢和肾功能相关指标均有显著改善。

结论

LSG、LSG+JJB和LRYGB在短期内均显示出显著的促进体重减轻和改善糖脂代谢的效果。术后,与术前相比,代谢综合征症状有所改善,LRYGB的效果优于LSG+JJB和LSG。

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