腹腔镜袖状胃切除术和腹腔镜Roux-en-Y胃旁路术的中长期效果的荟萃分析。
A meta-analysis of the medium- and long-term effects of laparoscopic sleeve gastrectomy and laparoscopic Roux-en-Y gastric bypass.
作者信息
Gu Lihu, Huang Xiaojing, Li Shengnan, Mao Danyi, Shen Zefeng, Khadaroo Parikshit Asutosh, Ng Derry Minyao, Chen Ping
机构信息
Department of General Surgery, HwaMei Hospital, University of Chinese Academy of Sciences, Northwest Street 41, Haishu District, Ningbo, Zhejiang, 315010, China.
The Second Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.
出版信息
BMC Surg. 2020 Feb 12;20(1):30. doi: 10.1186/s12893-020-00695-x.
BACKGROUND
Laparoscopic Roux-en-Y gastric bypass (LRYGB) and laparoscopic sleeve gastrectomy (LSG) are two representative bariatric surgeries. This study aimed to compare the effects of the LSG and LRYGB based on high-quality analysis and massive amount of data.
METHODS
For this study databases of PubMed, Web of Science, EBSCO, Medline, and Cochrane Library were searched for articles published until January 2019 comparing the outcomes of LSG and LRYGB.
RESULTS
This study included 28 articles. Overall, 9038 patients (4597, LSG group; 4441, LRYGB group) were included. The remission rate of type 2 diabetes mellitus (T2DM) in the LRYGB group was superior to that in the LSG group at the 3-years follow-up. Five-year follow-up results showed that LRYGB had an advantage over LSG for the percentage of excess weight loss and remission of T2DM, hypertension, dyslipidemia, and abnormally low-density lipoprotein.
CONCLUSIONS
In terms of the long-term effects of bariatric surgery, the effect of LRYGB was better than of LSG.
背景
腹腔镜Roux-en-Y胃旁路术（LRYGB）和腹腔镜袖状胃切除术（LSG）是两种具有代表性的减肥手术。本研究旨在基于高质量分析和大量数据比较LSG和LRYGB的效果。
方法
在本研究中，检索了PubMed、Web of Science、EBSCO、Medline和Cochrane图书馆数据库，以查找截至2019年1月发表的比较LSG和LRYGB结果的文章。
结果
本研究纳入了28篇文章。总体而言，共纳入9038例患者（LSG组4597例；LRYGB组4441例）。在3年随访时，LRYGB组2型糖尿病（T2DM）的缓解率优于LSG组。5年随访结果显示，在超重减轻百分比以及T2DM、高血压、血脂异常和低密度脂蛋白异常的缓解方面，LRYGB比LSG更具优势。
结论
就减肥手术的长期效果而言，LRYGB的效果优于LSG。
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