Luking Katherine R, Hennefield Laura, Ortin-Peralta Ana, Wright Amanda J, Whalen Diana J
Saint Louis University, St. Louis, Missouri.
Washington University in St. Louis School of Medicine, St. Louis, Missouri.
J Am Acad Child Adolesc Psychiatry. 2025 Jan 9. doi: 10.1016/j.jaac.2024.10.016.
The aim of this study was to determine whether advanced puberty at age 9 and 10 years, relative to that in same-aged peers, predicts current and/or new-onset self-injurious thoughts and behaviors (SITBs). New predictors of SITBs in preadolescence are urgently needed to address this escalating public health crisis of youth self-harm and suicidality.
Data from the baseline, 1-year, and 2-year waves of the Adolescent Brain and Cognitive Development Study were used. Bayesian mixed-effects models were estimated for test and replication split halves, and tested whether relatively advanced youth-reported pubertal development at 9 or 10 years predicted SITBs (suicidal ideation, suicide attempts, and non-suicidal self-injury) as reported by preadolescents (each wave) and their caregiver (baseline, 2-year follow-up) in a computerized version of the Kiddie Schedule for Affective Disorders and Schizophrenia (KSADS). Preadolescents with baseline self-reported puberty, KSADS (N = 8,708; 44.6% female; 60.8% White non-Hispanic), and demographic information were included.
Baseline preadolescent-reported puberty predicted the presence of any SITB before or at baseline (odds ratio = 1.50, 95% credible interval = 1.23-1.85) and the new-onset SITBs between baseline and 2-year follow-up in preadolescents SITB-naive at baseline (odds ratio = 2.26, 95% credible interval = 1.66-3.21).
Preadolescents reporting relatively advanced puberty were more likely to have experienced SITBs and, if SITB naive, were more likely to experience the onset of SITBs across the following 2 years. Findings were not explained by child psychopathology or other familial and psychosocial factors known to predict SITBs. Screening preadolescents for advanced puberty at ages 9 and 10 years and applying targeted suicide screening for those youth showing advanced puberty should be considered in primary care and mental health settings.
本研究旨在确定9岁和10岁时青春期提前相对于同龄同龄人而言,是否能预测当前和/或新出现的自伤性想法和行为(SITB)。迫切需要青春期前SITB的新预测因素,以应对青少年自我伤害和自杀行为这一日益严重的公共卫生危机。
使用青少年大脑与认知发展研究基线、1年和2年随访的数据。对测试和复制分割样本估计贝叶斯混合效应模型,并测试9岁或10岁时青少年报告的青春期发育相对提前是否能预测青春期前儿童(各随访期)及其照顾者(基线、2年随访)在计算机化的儿童情感障碍和精神分裂症量表(KSADS)中报告的SITB(自杀意念、自杀未遂和非自杀性自伤)。纳入了有基线自我报告青春期情况、KSADS数据(N = 8708;44.6%为女性;60.8%为非西班牙裔白人)以及人口统计学信息的青春期前儿童。
青春期前儿童在基线时报告的青春期发育情况可预测在基线时或之前是否存在任何SITB(优势比 = 1.50,95%可信区间 = 1.23 - 1.85),以及在基线时无SITB的青春期前儿童在基线和2年随访之间新出现的SITB(优势比 = 2.26,95%可信区间 = 1.66 - 3.21)。
报告青春期发育相对提前的青春期前儿童更有可能经历过SITB,并且如果在基线时无SITB,则在接下来的2年中更有可能出现SITB。研究结果不能用儿童精神病理学或其他已知可预测SITB的家庭和社会心理因素来解释。在初级保健和心理健康环境中,应考虑对9岁和10岁的青春期前儿童进行青春期提前筛查,并对那些显示青春期提前的青少年进行有针对性的自杀筛查。