女孩青春期发育时间提前的趋势及其可能机制
Trends Toward Earlier Puberty Timing in Girls and Its Likely Mechanisms.
作者信息
Cheng Tuck Seng, Ong Ken K, Biro Frank M
机构信息
MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge, United Kingdom; Department of Paediatrics, University of Cambridge, Cambridge Biomedical Campus, Box 116, Cambridge CB20QQ UK.
MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge, United Kingdom; Department of Paediatrics, University of Cambridge, Cambridge Biomedical Campus, Cambridge, United Kingdom.
出版信息
J Pediatr Adolesc Gynecol. 2022 Oct;35(5):527-531. doi: 10.1016/j.jpag.2022.04.009. Epub 2022 May 7.
This is the first of two installments examining early puberty in girls. The first paper will discuss secular trends in onset of puberty and the possible mechanisms to explain these developments. The potential etiologies examined will include the role of endocrine-disrupting chemicals and obesogens, the impact of body mass index and obesity, genetic and biologic pathways, and the influence of lifestyle behaviors. The second paper of the two-part series will examine the potential health impacts of early puberty on young and adult women and offer suggestions for clinical management and public health prevention.
这是关于女孩青春期早熟研究的两部分系列文章中的第一篇。第一篇论文将讨论青春期开始的长期趋势以及解释这些发展的可能机制。所探讨的潜在病因将包括内分泌干扰化学物质和致肥胖物的作用、体重指数和肥胖的影响、遗传和生物学途径以及生活方式行为的影响。这个两部分系列文章的第二篇论文将研究青春期早熟对年轻女性和成年女性的潜在健康影响，并为临床管理和公共卫生预防提供建议。
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