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美国高血压成年人每日步数与全因死亡率和心血管死亡率的关联:一项基于2005 - 2006年美国国家健康与营养检查调查(NHANES)的队列研究。

Associations of daily step count with all-cause mortality and cardiovascular mortality in hypertensive US adults: a cohort study from NHANES 2005-2006.

作者信息

Guo Tuo, Zhou Yang, Yang Guifang, Zhong Aifang, Pan Xiaogao, Pu Yuting, Simons Michael, Sheng Lijuan, Chai Xiangping

机构信息

Department of Emergency Medicine, The Second Xiangya Hospital, Central South University, Changsha, Hunan Province, China.

Emergency Medicine and Difficult Diseases Institute, Central South University, Changsha, Hunan Province, China.

出版信息

BMC Public Health. 2025 Jan 11;25(1):129. doi: 10.1186/s12889-024-21216-y.

DOI:10.1186/s12889-024-21216-y
PMID:39799282
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11725191/
Abstract

BACKGROUND

The health benefits of physical activity, including walking, are well-established, but the relationship between daily step count and mortality in hypertensive populations remains underexplored. This study investigates the association between daily step count and both all-cause and cardiovascular mortality in hypertensive American adults.

METHODS

We used data from the National Health and Nutrition Examination Survey 2005-2006, including 1,629 hypertensive participants with accelerometer-measured step counts. Cox proportional hazards models and restricted cubic spline regression were employed to assess the associations between daily step count and mortality outcomes. Analyses were adjusted for demographics, lifestyle factors, and comorbidities.

RESULTS

Over an average follow-up of 12.57 years, 370 deaths occurred, of which 177 were due to cardiovascular causes. We observed non-linear associations between daily step count and mortality. Mortality risks were significantly reduced with step counts to 8,250 steps/day for all-cause mortality and 9,700 steps/day for cardiovascular mortality. Beyond these thresholds, the benefits plateaued.

CONCLUSION

Increasing daily step count is associated with reduced all-cause and cardiovascular mortality in hypertensive individuals, with optimal benefits observed below 8,250 and 9,700 daily steps, respectively. Moderate levels of physical activity provide substantial health benefits, highlighting the importance of setting realistic and attainable activity goals for hypertensive populations.

摘要

背景

包括步行在内的体育活动对健康有益,这一点已得到充分证实,但高血压人群的每日步数与死亡率之间的关系仍未得到充分研究。本研究调查了美国高血压成年人的每日步数与全因死亡率和心血管死亡率之间的关联。

方法

我们使用了2005 - 2006年国家健康和营养检查调查的数据,其中包括1629名通过加速度计测量步数的高血压参与者。采用Cox比例风险模型和受限立方样条回归来评估每日步数与死亡率结果之间的关联。分析对人口统计学、生活方式因素和合并症进行了调整。

结果

在平均12.57年的随访期内,发生了370例死亡,其中177例是心血管原因导致的。我们观察到每日步数与死亡率之间存在非线性关联。全因死亡率方面,步数达到每天8250步时死亡风险显著降低,心血管死亡率方面,步数达到每天9700步时死亡风险显著降低。超过这些阈值后,益处趋于平稳。

结论

增加每日步数与高血压个体全因死亡率和心血管死亡率降低相关,分别在每日低于8250步和9700步时观察到最佳益处。适度的体育活动能带来显著的健康益处,凸显了为高血压人群设定现实且可实现的活动目标的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2563/11725191/44c35bb9a599/12889_2024_21216_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2563/11725191/b51a1adc4a15/12889_2024_21216_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2563/11725191/ef4b110706c8/12889_2024_21216_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2563/11725191/d3ca93b434ac/12889_2024_21216_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2563/11725191/44c35bb9a599/12889_2024_21216_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2563/11725191/b51a1adc4a15/12889_2024_21216_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2563/11725191/ef4b110706c8/12889_2024_21216_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2563/11725191/d3ca93b434ac/12889_2024_21216_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2563/11725191/44c35bb9a599/12889_2024_21216_Fig4_HTML.jpg

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