髓鞘少突胶质细胞糖蛋白抗体相关疾病（MOGAD）作为新发难治性癫痫持续状态（NORSE）的病因：病例报告及文献综述
Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) as a cause of new-onset refractory status epilepticus (NORSE): Case report and review of literature.
作者信息
Vaingankar Abhishek, Agarwal Ayush, Garg Divyani, Gupta Pranjal, Garg Ajay, Radhakrishnan Divya M, Pandit Awadh K, Srivastava Achal Kumar
机构信息
Department of Neurology, All India Institute of Medical Sciences, New Delhi, India.
Department of Neurology, All India Institute of Medical Sciences, New Delhi, India.
出版信息
J Neuroimmunol. 2025 Feb 15;399:578522. doi: 10.1016/j.jneuroim.2025.578522. Epub 2025 Jan 8.
Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) is a rare cause of NORSE. We describe the case of a young girl who presented with NORSE associated with MOGAD along with a systematic review of all cases of NORSE associated with MOGAD till date. Seizures associated with MOGAD are usually associated with good outcome but can occasionally be catastrophic and non-responsive to conventional therapies. Early initiation of anti-IL6 therapies might help improve outcomes in such patients.
髓鞘少突胶质细胞糖蛋白抗体相关疾病（MOGAD）是不明原因的癫痫性脑病（NORSE）的一种罕见病因。我们描述了一名年轻女孩的病例，她患有与MOGAD相关的NORSE，并对迄今为止所有与MOGAD相关的NORSE病例进行了系统回顾。与MOGAD相关的癫痫发作通常预后良好，但偶尔可能是灾难性的，对传统疗法无反应。早期启动抗IL6治疗可能有助于改善此类患者的预后。
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