Lee Chang Haur, Ong Yazid Pol, Hayati Firdaus, Muien Muhammad Zahid Abdul, Sharif Siti Zubaidah
Department of Surgery, Queen Elizabeth II Hospital, Ministry of Health Malaysia, Kota Kinabalu, Sabah, Malaysia.
Department of Otorhinolaryngology, Queen Elizabeth Hospital, Ministry of Health Malaysia, Kota Kinabalu, Sabah, Malaysia.
J Med Ultrasound. 2024 Jan 30;32(4):352-354. doi: 10.4103/jmu.jmu_32_23. eCollection 2024 Oct-Dec.
Thyroid hemiagenesis (THA) is a rare congenital abnormality in which one of the thyroid lobes fails to develop normally. The prevalence rates range from 0.02% to 0.25%, with no gender preponderance and most commonly involve the left lobe. We report a case of left THA in a 37-year-old female that was found incidentally during total thyroidectomy for right papillary thyroid carcinoma. Most patients with THA are asymptomatic, however, may have subclinically raised thyroid-stimulating hormone levels or be predisposed to developing thyroid disorders such as nodular goiter, hyperthyroidism, Grave's disease, Hashimoto's thyroiditis, hyperparathyroidism, or malignancy. Usual imaging techniques such as ultrasonography, computed tomography, and magnetic resonance imaging allow the confirmation of diagnosis and provide clearer glandular and regional visualization. Additional modalities such as thyroid scintigraphy enable the functional assessment and identification of any suspicious nodules and aid in decision-making. THA is a very uncommon condition and the diagnosis is primarily made through imaging. Clinicians should be aware that this condition exists along with documented associations of concomitant thyroid disorders and malignancy.
甲状腺半侧发育不全（THA）是一种罕见的先天性异常，其中甲状腺的一个叶未能正常发育。患病率在0.02%至0.25%之间，无性别倾向，最常累及左叶。我们报告一例37岁女性的左甲状腺半侧发育不全病例，该病例在因右甲状腺乳头状癌行全甲状腺切除术中偶然发现。大多数甲状腺半侧发育不全患者无症状，但可能有亚临床甲状腺刺激激素水平升高，或易患甲状腺疾病，如结节性甲状腺肿、甲状腺功能亢进、格雷夫斯病、桥本甲状腺炎、甲状旁腺功能亢进或恶性肿瘤。常用的影像学技术，如超声、计算机断层扫描和磁共振成像，可确诊并提供更清晰的腺体和区域可视化。其他检查方法，如甲状腺闪烁显像，可进行功能评估并识别任何可疑结节，有助于决策。甲状腺半侧发育不全是一种非常罕见的疾病，诊断主要通过影像学检查。临床医生应意识到这种疾病的存在以及与之相关的甲状腺疾病和恶性肿瘤。
