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使用胰岛素笔与胰岛素瓶/注射器的患者的满意度水平。一项前瞻性观察研究。

Level of Satisfaction Among Patients Using Insulin Administered by Pen vs Vial/Syringe. An Observational Prospective Study.

作者信息

Valladales-Restrepo Luis Fernando, Delgado-Araujo Ana Camila, Oyuela-Gutiérrez María Camila, Ospina-Arzuaga Harrison David, Machado-Alba Jorge Enrique

机构信息

Grupo de Investigación en Farmacoepidemiología y Farmacovigilancia, Universidad Tecnológica de Pereira-Audifarma S.A, Pereira, Risaralda, Colombia.

Grupo de Investigación Biomedicina, Facultad de Medicina, Fundación Universitaria Autónoma de las Américas, Pereira, Colombia.

出版信息

Patient Prefer Adherence. 2025 Jan 8;19:65-74. doi: 10.2147/PPA.S491944. eCollection 2025.

Abstract

PURPOSE

To determine the satisfaction of patients with diabetes mellitus who used subcutaneous insulin application devices in Colombia.

PATIENTS AND METHODS

An observational prospective study of patients with diabetes mellitus receiving insulin treatment in Colombia. Sociodemographic, comorbidity and pharmacological data were taken from a drug dispensing database. Through telephone calls, satisfaction with application devices was evaluated with Diabetes Treatment Satisfaction Questionnaire status version (DTSQ-s). Satisfaction was considered high at a score ≥30 points. The change in the type of insulin delivery device (ie, from pen to vial/syringe, and from vial/syringe to pen) was evaluated during a 1-year follow-up.

RESULTS

A total of 382 patients from 75 cities were selected, with a median age of 66.0 years, and 56.3% were women, and 65.2% were treated with long-acting insulins. The mean DTSQ-s score was 26.6±5.3 points, and 38.7% presented high satisfaction, without statistically significant differences between pen and vial/syringe. A total of 18.8% changed the administration device, mainly those that came from Bogotá-Cundinamarca (OR:2.19; 95% CI:1.01-4.75), in concomitant treatment with other antidiabetic drugs (OR:2.28; 95% CI:1.00-5.22) and those who previously used insulin in vial/syringe (OR:33.90; 95% CI:11.88-96.74).

CONCLUSION

The participants had low satisfaction with the insulin delivery device. No statistically significant differences were found in satisfaction between those who received pen vs vial/syringe insulin, and patients using the latter had a high probability of switching to insulin pen.

摘要

目的

确定在哥伦比亚使用皮下胰岛素注射装置的糖尿病患者的满意度。

患者与方法

对哥伦比亚接受胰岛素治疗的糖尿病患者进行一项前瞻性观察研究。社会人口统计学、合并症和药理学数据取自药物配给数据库。通过电话,使用糖尿病治疗满意度问卷状态版(DTSQ-s)评估对注射装置的满意度。得分≥30分被认为满意度高。在1年的随访期间评估胰岛素给药装置类型的变化(即从笔式注射器改为小瓶/注射器,以及从小瓶/注射器改为笔式注射器)。

结果

共选取了来自75个城市的382例患者,中位年龄为66.0岁,56.3%为女性,65.2%接受长效胰岛素治疗。DTSQ-s平均得分为26.6±5.3分,38.7%表现出高满意度,笔式注射器和小瓶/注射器之间无统计学显著差异。共有18.8%的患者更换了给药装置,主要是来自波哥大-昆迪纳马卡的患者(比值比:2.19;95%置信区间:1.01-4.75),正在接受其他抗糖尿病药物联合治疗的患者(比值比:2.28;95%置信区间:1.00-5.22),以及之前使用小瓶/注射器注射胰岛素的患者(比值比:33.90;95%置信区间:11.88-96.74)。

结论

参与者对胰岛素给药装置的满意度较低。接受笔式胰岛素与小瓶/注射器胰岛素治疗的患者在满意度上未发现统计学显著差异,使用后者的患者改用胰岛素笔的可能性较高。

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