Yang Chunyu, Wang Qi, Chen Shulin, Li Jinghua
Department of Materials Science and Engineering, The Ohio State University, Columbus, Ohio 43210, United States.
Chronic Brain Injury Program, The Ohio State University, Columbus, Ohio 43210, United States.
ACS Mater Au. 2024 Nov 20;5(1):45-56. doi: 10.1021/acsmaterialsau.4c00106. eCollection 2025 Jan 8.
The surge of flexible, biointegrated electronics has inspired continued research efforts in designing and developing chip-less and wireless devices as soft and mechanically compliant interfaces to the living systems. In recent years, innovations in materials, devices, and systems have been reported to address challenges surrounding this topic to empower their reliable operation for monitoring physiological signals. This perspective provides a brief overview of recent works reporting various chip-less electronics for sensing and actuation in diverse application scenarios. We summarize wireless signal/data/power transmission strategies, key considerations in materials design and selection, as well as successful demonstrations of sensors and actuators in wearable and implantable forms. The final section provides an outlook to the future direction down the road for performance improvement and optimization. These versatile, inexpensive, and low-power device concepts can serve as alternative strategies to existing digital wireless electronics, which will find broad applications as bidirectional biointerfaces in basic biomedical research and clinical practices.
柔性生物集成电子学的蓬勃发展激发了人们持续不断地开展研究工作，致力于设计和开发无芯片、无线的设备，使其作为与生命系统的柔软且机械柔顺的接口。近年来，已有关于材料、器件和系统方面的创新报道，以应对围绕该主题的挑战，从而实现其可靠运行以监测生理信号。本视角简要概述了近期报道的各种用于不同应用场景中传感与驱动的无芯片电子学研究成果。我们总结了无线信号/数据/功率传输策略、材料设计与选择中的关键考量因素，以及可穿戴和可植入形式的传感器与致动器的成功实例。最后一部分展望了未来性能提升与优化的发展方向。这些多功能、低成本且低功耗的器件概念可作为现有数字无线电子学的替代策略，在基础生物医学研究和临床实践中作为双向生物接口具有广泛的应用前景。
