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复发性自发性冠状动脉夹层作为反复心肌梗死的病因

Recurrent Spontaneous Coronary Artery Dissection as the Cause of Repeated Myocardial Infarctions.

作者信息

Knudsen Arnon Møldrup, Støttrup Nicolaj Brejnholt, Hager Henrik, Mølgaard Henning, Stilling Christina

机构信息

Department of Pathology Aarhus University Hospital Aarhus Denmark.

Department of Cardiology Aarhus University Hospital Aarhus Denmark.

出版信息

Clin Case Rep. 2025 Jan 10;13(1):e70083. doi: 10.1002/ccr3.70083. eCollection 2025 Jan.

Abstract

Spontaneous coronary artery dissection (SCAD) is characterized by intramural hematoma in a coronary artery leading to partial or complete vessel obstruction. A 51-year-old female was hospitalized with acute myocardial infarction and cardiogenic shock. She was diagnosed with severe SCAD, affecting the proximal left coronary artery. A complex percutaneous coronary intervention, complicated by cardiac arrest and need for cardio pulmonary support, succeeded with stent insertion and revascularization. In the following days, the patient developed severe heart failure due to extensive cardiac reperfusion injury and subsequently experienced multiple organ failure, ultimately resulting in death. The patient had previously been acutely hospitalized twice with myocardial infarctions and both the times was also diagnosed with SCAD affecting the left coronary artery. This case highlights an unfortunate patient outcome due to recurrent SCAD and serves as an important reminder to consider SCAD differential diagnostically in younger female patients with myocardial infarction.

摘要

自发性冠状动脉夹层(SCAD)的特征是冠状动脉壁内血肿导致部分或完全血管阻塞。一名51岁女性因急性心肌梗死和心源性休克入院。她被诊断为严重的SCAD,累及左冠状动脉近端。一次复杂的经皮冠状动脉介入治疗,并发心脏骤停且需要心肺支持,最终通过支架植入和血管重建成功完成。在接下来的几天里,患者因广泛的心脏再灌注损伤发展为严重心力衰竭,随后出现多器官功能衰竭,最终死亡。该患者此前曾因心肌梗死两次急性住院,两次均被诊断为累及左冠状动脉的SCAD。本病例凸显了复发性SCAD导致的不幸患者结局,并提醒我们在年轻女性心肌梗死患者中进行SCAD鉴别诊断的重要性。

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