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Sex, drugs and high fat diet: Characterizing HFpEF in female C57BL6/J mice.

作者信息

Travers Joshua, Robinson Emma L

机构信息

Department of Medicine, Division of Cardiology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.

Consortium for Fibrosis Research & Translation, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.

出版信息

J Mol Cell Cardiol Plus. 2024 Jan 23;7:100063. doi: 10.1016/j.jmccpl.2024.100063. eCollection 2024 Mar.

DOI:10.1016/j.jmccpl.2024.100063
PMID:39802440
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11708410/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a0b8/11708410/785a2e42ba77/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a0b8/11708410/785a2e42ba77/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a0b8/11708410/785a2e42ba77/gr1.jpg

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1
Sex, drugs and high fat diet: Characterizing HFpEF in female C57BL6/J mice.性别、药物与高脂饮食:对雌性C57BL6/J小鼠的射血分数保留的心力衰竭进行特征描述
J Mol Cell Cardiol Plus. 2024 Jan 23;7:100063. doi: 10.1016/j.jmccpl.2024.100063. eCollection 2024 Mar.
2
Strain dependence of diet-induced NASH and liver fibrosis in obese mice is linked to diabetes and inflammatory phenotype.肥胖小鼠饮食诱导的非酒精性脂肪性肝炎和肝纤维化的品系依赖性与糖尿病和炎症表型有关。
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Two-hit mouse model of heart failure with preserved ejection fraction combining diet-induced obesity and renin-mediated hypertension.结合饮食诱导肥胖和肾素介导高血压的射血分数保留型心力衰竭双打击小鼠模型。
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本文引用的文献

1
Unveiling the vulnerability of C57BL/6J female mice to HFpEF and its related complications.揭示C57BL/6J雌性小鼠对射血分数保留的心力衰竭及其相关并发症的易感性。
J Mol Cell Cardiol Plus. 2024 Mar;7. doi: 10.1016/j.jmccpl.2024.100062. Epub 2024 Jan 12.
2
Sex differences in heart mitochondria regulate diastolic dysfunction.心脏线粒体中的性别差异调节舒张功能障碍。
Nat Commun. 2022 Jul 4;13(1):3850. doi: 10.1038/s41467-022-31544-5.
3
Global burden of heart failure: a comprehensive and updated review of epidemiology.心力衰竭的全球负担:流行病学的全面更新综述
Cardiovasc Res. 2023 Jan 18;118(17):3272-3287. doi: 10.1093/cvr/cvac013.
4
Empagliflozin in Heart Failure with a Preserved Ejection Fraction.恩格列净治疗射血分数保留的心力衰竭。
N Engl J Med. 2021 Oct 14;385(16):1451-1461. doi: 10.1056/NEJMoa2107038. Epub 2021 Aug 27.
5
Renal Dysfunction and Heart Failure with Preserved Ejection Fraction.肾功能障碍和射血分数保留的心力衰竭。
Heart Fail Clin. 2021 Jul;17(3):357-367. doi: 10.1016/j.hfc.2021.03.005.
6
The effects of liraglutide and dapagliflozin on cardiac function and structure in a multi-hit mouse model of heart failure with preserved ejection fraction.利拉鲁肽和达格列净对射血分数保留的心力衰竭多因素打击小鼠模型心功能和结构的影响。
Cardiovasc Res. 2021 Jul 27;117(9):2108-2124. doi: 10.1093/cvr/cvaa256.
7
Female Sex Is Protective in a Preclinical Model of Heart Failure With Preserved Ejection Fraction.在射血分数保留的心力衰竭临床前模型中,女性具有保护作用。
Circulation. 2019 Nov 19;140(21):1769-1771. doi: 10.1161/CIRCULATIONAHA.119.042267. Epub 2019 Nov 18.
8
Mouse Vendor Influence on the Bacterial and Viral Gut Composition Exceeds the Effect of Diet.老鼠供应商对肠道细菌和病毒组成的影响超过了饮食的影响。
Viruses. 2019 May 13;11(5):435. doi: 10.3390/v11050435.
9
Nitrosative stress drives heart failure with preserved ejection fraction.硝化应激导致射血分数保留型心力衰竭。
Nature. 2019 Apr;568(7752):351-356. doi: 10.1038/s41586-019-1100-z. Epub 2019 Apr 10.
10
A Feline HFpEF Model with Pulmonary Hypertension and Compromised Pulmonary Function.一种伴有肺动脉高压和肺功能受损的猫心衰伴射血分数保留模型。
Sci Rep. 2017 Nov 29;7(1):16587. doi: 10.1038/s41598-017-15851-2.