Machnik Domenique, Fischer Sarah, Vetter Marcel, Lamprecht-Bailer Ricarda, Rouse-Merkel Rachel, Klett Daniel, Neurath Markus F, Strobel Deike, Zundler Sebastian, Haberkamp Sophie
Department of Medicine 1, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
Department of Medicine 1, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Ulmenweg 18, Erlangen 91054, Germany.
Therap Adv Gastroenterol. 2025 Jan 10;18:17562848241310183. doi: 10.1177/17562848241310183. eCollection 2025.
Medically intractable ascites causes substantial distress in patients with palliative disease. Tunneled peritoneal catheters have been established as a feasible treatment option allowing patient-controlled paracentesis in a homecare setting. However, while a range of complications is associated with these drainages, risk factors for complications have not been identified so far.
To explore potential risk factors associated with complications of tunneled peritoneal catheters.
Retrospective observational cohort study.
Single-center cohort comprising 49 patients with palliative disease receiving 57 tunneled peritoneal catheters at a tertiary care hospital.
Catheter placement was successful in all patients and associated with low numbers of severe complications. Our data suggest a higher risk for severe late complications in patients with benign disease, with drainage replacement, and when performed by less experienced physicians.
Tunneled peritoneal catheters are an effective and safe option to treat symptomatic ascites in patients with end-stage palliative disease. The indication should be carefully considered in patients with benign disease and after removal or dislocation of a previous catheter.
内科治疗无效的腹水给姑息治疗患者带来极大痛苦。隧道式腹膜导管已被确立为一种可行的治疗选择，可让患者在家庭护理环境中进行自控腹腔穿刺放液。然而，尽管这些引流存在一系列并发症，但迄今为止尚未确定并发症的危险因素。
探讨与隧道式腹膜导管并发症相关的潜在危险因素。
回顾性观察队列研究。
在一家三级护理医院，对49例接受57根隧道式腹膜导管的姑息治疗患者组成的单中心队列进行研究。
所有患者导管置入均成功，且严重并发症数量较少。我们的数据表明，良性疾病患者、进行引流置换以及由经验较少的医生操作时，发生严重晚期并发症的风险更高。
隧道式腹膜导管是治疗终末期姑息治疗患者症状性腹水的有效且安全的选择。对于良性疾病患者以及先前导管拔除或移位后，应谨慎考虑适应证。
