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口香糖对结直肠癌手术后肠道活动恢复的影响。

The Effect of Chewing Gum on the Return of Bowel Activity after Colorectal Cancer Surgery.

作者信息

Zargar Talha, Wagay Bilal A, Banday Imad, Haq Mohd Fazlul, Parray Fazl Q, Banday Meeran, Hamdani Hanna Zahoor

机构信息

Department of General and Minimal Invasive Surgery, Sher-I-Kashmir Institute of Medical Sciences, Srinagar, Kashmir, India.

Department of Radiodiagnosis and Imaging, Acharya Shri Chander College of Medical Sciences and Hospital, Sidhra, Jammu, India.

出版信息

Euroasian J Hepatogastroenterol. 2024 Jul-Dec;14(2):210-213. doi: 10.5005/jp-journals-10018-1456. Epub 2024 Dec 27.

DOI:10.5005/jp-journals-10018-1456
PMID:39802852
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11714110/
Abstract

BACKGROUND

Enhanced recovery after surgery (ERAS) protocols advocate for early enteral feeding to prevent postoperative ileus. Chewing gum acts as a type of sham feeding that triggers the cephalic phase of digestion by stimulating the cephalic vagus nerve. This can enhance gastrointestinal motility and may lead to quicker recovery of gas and bowel movements.

OBJECTIVES

To assess how chewing gum during the early postoperative phase affects the duration of postoperative ileus in terms of time to appreciation of first flatus, time to passage of first stools, and duration of hospital stay.

MATERIALS AND METHODS

The study was conducted in our division of colorectal surgery. This is a case-control study carried out over three years (2020-2023). A total of 100 patients were included, the first 50 were allocated to the control group, and another 50 were allocated to the chewing gum group. All patients above the age of 14 years who underwent resection for colorectal cancers were included.

RESULTS

The average age in the control group was 51.44 years and that in the chewing gum group was 50.04 years. The average duration of surgery for the control group was 156.3 minutes (2.6 hours) and 163.8 minutes (2.7 hours) in the chewing gum group. The average time of passage of the first flatus in the chewing gum group was 51.28 hours compared to 66.26 hours in the control group ( = 0.0002). The average time to first bowel movement in the chewing gum group was 71.42 hours. In comparison, the time to first bowel movement in the control group was 85.78 hours ( = 0.000011). The average hospital stay in the chewing gum group was 6.3 days and that in the control group was 6.4 days ( = 0.274254).

CONCLUSION

Chewing gum as a means of sham feeding is a cost-friendly method that significantly decreases the postoperative ileus but has no effect on postoperative hospital stay.

HOW TO CITE THIS ARTICLE

Zargar T, Wagay BA, Banday I, The Effect of Chewing Gum on the Return of Bowel Activity after Colorectal Cancer Surgery. Euroasian J Hepato-Gastroenterol 2024;14(2):210-213.

摘要

背景

术后加速康复(ERAS)方案提倡早期肠内喂养以预防术后肠梗阻。口香糖作为一种假饲方式,通过刺激迷走神经的头端部分触发消化的头期。这可以增强胃肠动力,并可能导致更快恢复排气和排便。

目的

评估术后早期嚼口香糖对术后肠梗阻持续时间的影响,包括首次排气时间、首次排便时间和住院时间。

材料与方法

本研究在我们的结直肠外科进行。这是一项为期三年(2020 - 2023年)的病例对照研究。共纳入100例患者,前50例分配到对照组,另外50例分配到口香糖组。纳入所有14岁以上接受结直肠癌切除术的患者。

结果

对照组的平均年龄为51.44岁,口香糖组为50.04岁。对照组的平均手术时长为156.3分钟(2.6小时),口香糖组为163.8分钟(2.7小时)。口香糖组首次排气的平均时间为51.28小时,而对照组为66.26小时(P = 0.0002)。口香糖组首次排便的平均时间为71.42小时。相比之下,对照组首次排便的时间为85.78小时(P = 0.000011)。口香糖组的平均住院时间为6.3天,对照组为6.4天(P = 0.274254)。

结论

嚼口香糖作为一种假饲方式是一种经济实惠的方法,可显著减少术后肠梗阻,但对术后住院时间无影响。

如何引用本文

扎尔加尔T、瓦盖BA、班迪I,口香糖对结直肠癌手术后肠道活动恢复的影响。《欧亚肝脏胃肠病学杂志》2024;14(2):210 - 213。

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本文引用的文献

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Int J Surg. 2017 Nov;47:107-115. doi: 10.1016/j.ijsu.2017.07.107. Epub 2017 Sep 1.
2
Efficacy of Gum Chewing on Bowel Movement After Open Colectomy for Left-Sided Colorectal Cancer: A Randomized Clinical Trial.咀嚼口香糖对左侧结直肠癌开放结肠切除术后排便的影响:一项随机临床试验
Dis Colon Rectum. 2015 Nov;58(11):1058-63. doi: 10.1097/DCR.0000000000000452.
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Sham feeding with chewing gum after elective colorectal resectional surgery: a randomized clinical trial.择期结直肠切除术后咀嚼口香糖行假饲:一项随机临床试验。
Ann Surg. 2013 Jun;257(6):1016-24. doi: 10.1097/SLA.0b013e318286504a.
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Defining postoperative ileus: results of a systematic review and global survey.定义术后肠梗阻:系统评价和全球调查的结果。
J Gastrointest Surg. 2013 May;17(5):962-72. doi: 10.1007/s11605-013-2148-y. Epub 2013 Feb 2.
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Current therapies to shorten postoperative ileus.目前缩短术后肠梗阻的治疗方法。
Cleve Clin J Med. 2009 Nov;76(11):641-8. doi: 10.3949/ccjm.76a.09051.
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Perioperative strategy in colonic surgery; LAparoscopy and/or FAst track multimodal management versus standard care (LAFA trial).结肠手术的围手术期策略;腹腔镜和/或快速多模式管理与标准护理(LAFA试验)
BMC Surg. 2006 Nov 29;6:16. doi: 10.1186/1471-2482-6-16.
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Review of the pathophysiology and management of postoperative ileus.术后肠梗阻的病理生理学及管理综述。
World J Surg. 2006 Aug;30(8):1382-91. doi: 10.1007/s00268-005-0613-9.
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Gum chewing reduces ileus after elective open sigmoid colectomy.咀嚼口香糖可减少择期开放性乙状结肠切除术后的肠梗阻。
Arch Surg. 2006 Feb;141(2):174-6. doi: 10.1001/archsurg.141.2.174.
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