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北比哈尔邦新诊断2型糖尿病患者中的非酒精性脂肪性肝病及早期诊断的错失机会

Non-Alcoholic Fatty Liver Disease Among Newly Diagnosed Type 2 Diabetes Mellitus in North Bihar and Missed Opportunities for Early Diagnosis.

作者信息

Mukherjee Supriyo, Mukherjee Bishnupriya, Goswami Anjali, Kwok Chun Shing, Phillips Anne

机构信息

Department of Medicine, Dr Mukherjee S Clinic Pvt. Ltd. and Research Centre for Diabetes Hypertension and Obesity (RCDHO), Samastipur, IND.

Department of Medicine, Research Centre for Diabetes Hypertension and Obesity (RCDHO), Samastipur, IND.

出版信息

Cureus. 2024 Dec 13;16(12):e75661. doi: 10.7759/cureus.75661. eCollection 2024 Dec.

DOI:10.7759/cureus.75661
PMID:39803023
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11725303/
Abstract

BACKGROUND

There are no studies investigating missed opportunities for earlier diagnosis in newly/recently detected Type 2 Diabetes Mellitus and Non-alcoholic Fatty Liver Disease in the region of Bihar, India.

METHODS

This study is a single-center cross-sectional study undertaken at the Research Centre for Diabetes Hypertension and Obesity, Samastipur, Bihar, India. The study collected data from newly/recently diagnosed persons with T2DM. The study was conducted between December 2022 and May 2023.

RESULTS

A total of 148 people with newly diagnosed T2DM were included (median age 47, 46.6% female), and 109 patients with liver disease on ultrasound evaluation. The majority of the persons detected with diabetes were symptomatic. The commonest group of typical symptoms were excessive hunger, urinary frequency, excessive thirst, and evening fatigue, which were present in 46 individuals with liver disease. The best pathway includes a group of persons who visited specialists and MBBS doctors once they felt their symptoms should be evaluated by them and diagnosed within two months of their symptom onset. Unfavorable pathways causing delays in diagnosis and hindering efficient care involve individuals with diabetes seeking help from village doctors, pharmacists, and Aayush doctors, thereby contributing to missed opportunities.

CONCLUSION

NAFLD is prevalent in new T2DM, especially among those with high fat intake and obesity markers. This study could initiate future research aiming to improve NAFLD management and decrease associated complications in newly diagnosed persons with T2DM.

摘要

背景

在印度比哈尔邦地区,尚无关于新诊断/近期诊断的2型糖尿病和非酒精性脂肪性肝病早期诊断错失机会的研究。

方法

本研究是一项在印度比哈尔邦萨马斯蒂布尔糖尿病高血压与肥胖研究中心进行的单中心横断面研究。该研究收集了新诊断/近期诊断的2型糖尿病患者的数据。研究于2022年12月至2023年5月进行。

结果

共纳入148例新诊断的2型糖尿病患者(中位年龄47岁,女性占46.6%),109例经超声评估患有肝病的患者。大多数检测出糖尿病的患者有症状。最常见的典型症状组为饥饿感过强、尿频、口渴过度和傍晚疲劳,46例肝病患者出现这些症状。最佳途径包括一组患者,他们在感觉症状应由专科医生和医学学士医生评估后就诊,并在症状出现后两个月内得到诊断。导致诊断延迟并阻碍有效治疗的不良途径包括糖尿病患者向乡村医生、药剂师和阿育吠陀医生寻求帮助,从而造成错失机会。

结论

非酒精性脂肪性肝病在新诊断的2型糖尿病中普遍存在,尤其是在高脂肪摄入和有肥胖标志物的人群中。本研究可为未来旨在改善新诊断的2型糖尿病患者非酒精性脂肪性肝病管理并减少相关并发症的研究提供开端。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65c3/11725303/6e1dccf0e54f/cureus-0016-00000075661-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65c3/11725303/b01aa3b150b3/cureus-0016-00000075661-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65c3/11725303/77464f5de3a8/cureus-0016-00000075661-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65c3/11725303/ddb1410f8a66/cureus-0016-00000075661-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65c3/11725303/6e1dccf0e54f/cureus-0016-00000075661-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65c3/11725303/b01aa3b150b3/cureus-0016-00000075661-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65c3/11725303/77464f5de3a8/cureus-0016-00000075661-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65c3/11725303/ddb1410f8a66/cureus-0016-00000075661-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65c3/11725303/6e1dccf0e54f/cureus-0016-00000075661-i04.jpg

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本文引用的文献

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