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一名儿童因大环内酯类耐药导致气道阻塞的坏死性支气管炎:病例报告

Necrotizing Bronchitis with Airway Obstruction Due to Macrolide-Resistant in a Child: A Case Report.

作者信息

Li Zhongjie, Xu Yao, Xiang Yujian

机构信息

Department of Pediatrics, Zhejiang University School of Medicine Second Affiliated Hospital Jiashan Branch, the First People's Hospital of Jiashan, Jiashan, Zhejiang, 314100, People's Republic of China.

出版信息

Infect Drug Resist. 2025 Jan 6;18:77-82. doi: 10.2147/IDR.S498411. eCollection 2025.

Abstract

Although infection with is generally self-limited, it may cause refractory or life-threatening pneumonia with pulmonary or extrapulmonary complications. Necrotizing bronchitis is a rare condition with a high mortality rate. The present report describes a patient with mycoplasma pneumonia and necrotizing bronchitis that caused airway obstruction. A 7-year-old girl presented with fever and cough and was hospitalized. Her symptoms did not improve, and mild hypoxemia was observed. Fiberoptic bronchoscopy revealed diffuse bronchitis with necrotic and hemorrhagic material obstructing the bronchus. The necrotic tissue was removed directly, unblocking the airways. This case underscores the importance of fiberoptic bronchoscopy for early diagnosis and treatment of severe respiratory complications associated with Mycoplasma pneumoniae infection, such as necrotizing bronchitis. Early recognition and timely intervention are critical to improving patient outcomes in such cases.

摘要

虽然感染通常是自限性的,但它可能导致难治性或危及生命的肺炎,并伴有肺部或肺外并发症。坏死性支气管炎是一种罕见的疾病,死亡率很高。本报告描述了一名患有支原体肺炎和坏死性支气管炎并导致气道阻塞的患者。一名7岁女孩因发热和咳嗽入院。她的症状没有改善,并观察到轻度低氧血症。纤维支气管镜检查显示弥漫性支气管炎,坏死和出血性物质阻塞支气管。直接清除坏死组织,疏通气道。该病例强调了纤维支气管镜检查对于早期诊断和治疗与肺炎支原体感染相关的严重呼吸并发症(如坏死性支气管炎)的重要性。在此类病例中,早期识别和及时干预对于改善患者预后至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ac7/11721681/779273e543d4/IDR-18-77-g0001.jpg

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