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茚虫威与虱螨脲急性混合中毒病例报告及其处理

A case report on acute combined poisoning of Indoxacarb and Novoluron and its management.

作者信息

Chitithoti Rohita, Sai Supraja Chopparapu, Sreelekha Danaboyina, Adusumilli Sri Lakshmi Sai Meghana, Veerareddy Ramireddy, Santosh Puppala

机构信息

Department of General Medicine, NRI Medical College, Chinakakani, Guntur, India.

出版信息

SAGE Open Med Case Rep. 2025 Jan 11;13:2050313X241307682. doi: 10.1177/2050313X241307682. eCollection 2025.

Abstract

In India, it is not uncommon for individuals to attempt suicide by ingesting pesticides. Though several publications have reported cases, there are no specific guidelines for managing indoxacarb poisoning. There is no established antidote for indoxacarb poisoning; however, early recognition and treatment of methemoglobinaemia, the primary manifestation, is essential. Early intervention is crucial for a positive outcome. Methemoglobinaemia can be successfully treated with methylene blue, which serves as the first line of management. This case report describes a 24-year-old man presenting with methemoglobinaemia following the ingestion of indoxacarb combined with novaluron and was successfully treated with early administration of methylene blue, leading to rapid recovery despite a methaemoglobin level as high as 75%.

摘要

在印度,个人通过摄入杀虫剂企图自杀的情况并不罕见。尽管有几篇出版物报道了相关病例,但对于茚虫威中毒的处理尚无具体指南。目前尚无针对茚虫威中毒的确立解毒剂;然而,对主要表现高铁血红蛋白血症的早期识别和治疗至关重要。早期干预对于取得良好结果至关重要。高铁血红蛋白血症可用亚甲蓝成功治疗,亚甲蓝是一线治疗药物。本病例报告描述了一名24岁男性,在摄入茚虫威与虱螨脲混合剂后出现高铁血红蛋白血症,通过早期给予亚甲蓝成功治疗,尽管高铁血红蛋白水平高达75%,仍实现了快速康复。

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A case report on acute combined poisoning of Indoxacarb and Novoluron and its management.茚虫威与虱螨脲急性混合中毒病例报告及其处理
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Indoxacarb poisoning presenting as methemoglobinemia: A case report.以高铁血红蛋白血症为表现的茚虫威中毒:一例报告。
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本文引用的文献

1
Indoxacarb poisoning presenting as methemoglobinemia: A case report.以高铁血红蛋白血症为表现的茚虫威中毒:一例报告。
Int J Crit Illn Inj Sci. 2024 Jan-Mar;14(1):59-61. doi: 10.4103/ijciis.ijciis_37_23. Epub 2024 Mar 27.
3
Methemoglobinemia Caused by Indoxacarb Poisoning.茚虫威中毒引起的高铁血红蛋白血症
Am J Med Sci. 2017 Jun;353(6):603-604. doi: 10.1016/j.amjms.2016.08.004. Epub 2016 Aug 11.
6
Methylene blue unresponsive methemoglobinemia.亚甲蓝无反应性高铁血红蛋白血症
Indian J Crit Care Med. 2014 Apr;18(4):253-5. doi: 10.4103/0972-5229.130582.
7
Methemoglobinemia associated with metaflumizone poisoning.与甲呋酰胺中毒相关的高铁血红蛋白血症。
Clin Toxicol (Phila). 2014 Apr;52(4):288-90. doi: 10.3109/15563650.2014.900180. Epub 2014 Mar 20.

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