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登革热眼部表现的最新情况。

An update on the ocular manifestations of dengue.

作者信息

Wang Christina, Castillo Arturo, Cortes-Bejarano Federico, Lopez Eduardo, de Souza Eduardo Cunha, Wu Lihteh

机构信息

Asociados de Macula, Vitreo y Retina de Costa Rica, Primer Piso Torre Mercedes Paseo Colon, San Jose, Costa Rica.

出版信息

Taiwan J Ophthalmol. 2024 Jan 9;14(4):540-547. doi: 10.4103/tjo.TJO-D-23-00106. eCollection 2024 Oct-Dec.

Abstract

Dengue is the most common arboviral disease. It is typically spread by the bite of an infected female or mosquitoes. Dengue is endemic in subtropical and tropical regions, but its geographic reach keeps expanding. Ophthalmic manifestations of dengue are common and may present with a wide spectrum of ophthalmic findings. These may range from conjunctival petechiae, retinal hemorrhage, retinal vasculitis to panophthalmitis. Some of these may be vision threatening and may require urgent ophthalmic evaluation. The precise pathophysiologic mechanisms involved in dengue infection involve a complex interplay between host immune responses, virus, and host genes. There is no specific treatment for ocular dengue. Therefore, treatment is supportive. Despite the lack of proven efficacy, corticosteroids have been used in vision-threatening dengue-related ocular complications. Dengue must be considered in endemic areas, and a careful travel history needs to be elicited in nonendemic areas.

摘要

登革热是最常见的虫媒病毒病。它通常通过受感染的雌性伊蚊叮咬传播。登革热在亚热带和热带地区呈地方性流行,但其地理范围不断扩大。登革热的眼部表现很常见,可能会出现广泛的眼科检查结果。这些表现可能包括结膜瘀点、视网膜出血、视网膜血管炎到全眼球炎。其中一些可能会威胁视力,可能需要紧急眼科评估。登革热感染所涉及的精确病理生理机制涉及宿主免疫反应、病毒和宿主基因之间的复杂相互作用。眼部登革热没有特效治疗方法。因此,治疗以支持治疗为主。尽管缺乏已证实的疗效,但皮质类固醇已被用于治疗威胁视力的登革热相关眼部并发症。在流行地区必须考虑登革热,在非流行地区需要仔细询问旅行史。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f72/11717331/b60eb8ac91e6/TJO-14-540-g001.jpg

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