Jareonsettasin Prem, Sander Josemir W
UCL Queen Square Institute of Neurology, London WC1N 3BG, & Chalfont Centre for Epilepsy, Chalfont St Peter SL9 0RJ, UK.
SdHIELD (Social determinants of Health In EpiLeptic Disorders) Research Group, London, United Kingdom.
Turk Arch Pediatr. 2025 Jan 2;60(1):13-21. doi: 10.5152/TurkArchPediatr.2025.24271.
Social determinants of health (SDHs) are significant and potentially modifiable drivers of neurologic diseases, including childhood epilepsy. Social determinants of health greatly influence the epidemiology, management, and outcomes associated with these conditions. Social determinants of health affect every aspect of a family's journey with epilepsy-from initial diagnosis to accessing effective treatments and ongoing care. Despite notable advancements in understanding the genetic and molecular underpinnings of pediatric epilepsies, there remains a relative lack of knowledge about the nature and impact of SDHs on these disorders. Epilepsy is a symptom of much more profound underlying determinants of health. Addressing the broader context of epilepsy can transform health outcomes. This narrative review appraises some available evidence and explores possible solutions.
健康的社会决定因素（SDH）是包括儿童癫痫在内的神经系统疾病的重要且可能可改变的驱动因素。健康的社会决定因素极大地影响这些疾病的流行病学、管理和结局。健康的社会决定因素影响着家庭与癫痫抗争历程的方方面面——从最初诊断到获得有效治疗以及持续护理。尽管在理解小儿癫痫的遗传和分子基础方面取得了显著进展，但对于健康的社会决定因素对这些疾病的性质和影响仍相对缺乏了解。癫痫是更深刻的潜在健康决定因素的一种症状。解决癫痫的更广泛背景问题可以改变健康结局。这篇叙述性综述评估了一些现有证据并探索了可能的解决方案。
