Çakmak Eda, Kılıç Serhat, Özdemir Pınar, Karaağaoğlu Ergun
Department of Audiology, Başkent University Faculty of Health Sciences, Ankara, Türkiye.
Department of Pediatrics, Başkent University Faculty of Medicine, Ankara, Türkiye.
Turk Arch Pediatr. 2025 Jan 2;60(1):63-70. doi: 10.5152/TurkArchPediatr.2025.24180.
Objective: Growth curves are important tools for assessing the growth and development of children in the target population by age. Measuring head circumference (HC) in infants is an important tool in monitoring infant health and brain development. The aims of this study are to construct current 0-2-year-old HC growth curves and percentiles and compare the methods used in the construction of growth curves for HC measurements by gender. Materials and Methods: The study is a retrospective research that includes the HC measurements of a total of 2832 (n = 1438 girls, n = 1394 boys) children examined between 2018 and 2021 in Başkent University hospital, Ankara. Lambda-Mu-Sigma, LMSP, and LMST methods based on Box-Cox Cole and Green (BCCG), Box-Cox power exponential (BCPE), and Box-Cox t (BCT) distributions respectively, and quantile regression (QR) method were used to construct the fitted growth curves. Model performances were evaluated using the generalized Akaike information criterion. The analyses were conducted using R 4.1.2 version. Results: According to the LMS and QR methods, percentile values of HC measurements by gender were calculated and the results were compared. Smoothed HC growth curves were constructed and compared for both methods by gender. The present study, Neyzi et al study, and World Health Organization (WHO) standards were compared for the third, 50th and 97th percentiles of HC. Conclusion: This study showed that the third-97th HC percentiles calculated by LMS and QR methods are very close to each other. Additionally, this study showed that the HC percentiles of Turkish children were slightly different compared to WHO standards.
生长曲线是按年龄评估目标人群中儿童生长发育的重要工具。测量婴儿头围（HC）是监测婴儿健康和大脑发育的重要手段。本研究的目的是构建当前0至2岁儿童的头围生长曲线和百分位数，并比较构建头围测量生长曲线时按性别使用的方法。材料与方法：本研究为回顾性研究，纳入了2018年至2021年期间在安卡拉巴什肯特大学医院接受检查的2832名儿童（n = 1438名女孩，n = 1394名男孩）的头围测量数据。分别基于Box-Cox Cole和Green（BCCG）分布、Box-Cox幂指数（BCPE）分布以及Box-Cox t（BCT）分布的Lambda-Mu-Sigma、LMSP和LMST方法，以及分位数回归（QR）方法被用于构建拟合生长曲线。使用广义赤池信息准则评估模型性能。分析使用R 4.1.2版本进行。结果：根据LMS和QR方法，计算了按性别划分的头围测量百分位数值并比较了结果。构建了按性别划分的两种方法的平滑头围生长曲线并进行了比较。将本研究、内齐等人的研究以及世界卫生组织（WHO）标准对头围的第3、50和97百分位数进行了比较。结论：本研究表明，通过LMS和QR方法计算的第3至97头围百分位数彼此非常接近。此外，本研究表明，土耳其儿童的头围百分位数与WHO标准相比略有不同。
