Wachtel Lee, Luccarelli James, Falligant John Michael, Smith Joshua Ryan
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine.
Kennedy Krieger Institute, Baltimore, Maryland.
Curr Opin Psychiatry. 2025 Mar 1;38(2):79-86. doi: 10.1097/YCO.0000000000000985. Epub 2024 Dec 20.
Over the last quarter century, the clinical evidence surrounding the use of electroconvulsive therapy (ECT) in individuals with autism spectrum disorder (ASD) has expanded. This review provides the most up-to-date findings on the usage of ECT in ASD and discusses these results within the historical context and direct patient care experience.
ECT is typically implemented for psychotropic-refractory catatonic, affective, psychotic, and combined pathology for individuals across the lifespan. Although highly stigmatized, ECT is well tolerated, efficacious, and potentially lifesaving for select individuals. A case presentation of an individual with autism as well as a summary of legal restrictions hampering his ECT access is presented.
ECT is increasingly used in individuals with ASD who present with a wide range of ECT-responsive psychopathology, as well as repetitive self-injury and late, autistic-like regression for which no cause is found. ECT is well tolerated and offers real hope for many ASD individuals with devastating, treatment-refractory conditions.
在过去二十五年中，关于在自闭症谱系障碍（ASD）患者中使用电休克疗法（ECT）的临床证据有所增加。本综述提供了关于ECT在ASD中使用的最新研究结果，并在历史背景和直接的患者护理经验中讨论了这些结果。
ECT通常用于各年龄段患有精神药物难治性紧张症、情感障碍、精神病及合并病症的患者。尽管ECT存在高度污名化，但它耐受性良好、疗效显著，对某些患者可能具有挽救生命的作用。本文呈现了一例自闭症患者的病例介绍以及阻碍其接受ECT治疗的法律限制总结。
ECT越来越多地用于患有多种ECT反应性精神病理学的ASD患者，以及重复性自我伤害和原因不明的迟发性、类似自闭症的退化患者。ECT耐受性良好，为许多患有严重、治疗难治性疾病的ASD患者带来了真正的希望。
