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Major cell types in the coronary thrombosis of acute myocardial infarction patients revealed by scRNA-seq.

作者信息

Wei Zhiyao, Cui Cheng, Li Zixuan, Li Jianping, Shao Yibing, Wang Jizheng, Guo Jincheng, Song Lei

机构信息

State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

Division of Cardiology, Fuwai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

出版信息

Clin Transl Med. 2025 Jan;15(1):e70181. doi: 10.1002/ctm2.70181.

DOI:10.1002/ctm2.70181
PMID:39804415
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11727574/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6a8/11727574/ae985bb88af2/CTM2-15-e70181-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6a8/11727574/a0db1a32e597/CTM2-15-e70181-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6a8/11727574/939045abf537/CTM2-15-e70181-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6a8/11727574/ae985bb88af2/CTM2-15-e70181-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6a8/11727574/a0db1a32e597/CTM2-15-e70181-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6a8/11727574/939045abf537/CTM2-15-e70181-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6a8/11727574/ae985bb88af2/CTM2-15-e70181-g003.jpg

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本文引用的文献

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Examining the function of macrophage oxidative stress response and immune system in glioblastoma multiforme through analysis of single-cell transcriptomics.通过单细胞转录组学分析研究巨噬细胞氧化应激反应和免疫系统在多形性胶质母细胞瘤中的作用。
Front Immunol. 2024 Jan 11;14:1288137. doi: 10.3389/fimmu.2023.1288137. eCollection 2023.
2
Inflammation in acute myocardial infarction: the good, the bad and the ugly.急性心肌梗死中的炎症:有好有坏有丑恶。
Eur Heart J. 2024 Jan 7;45(2):89-103. doi: 10.1093/eurheartj/ehad486.
3
Dynamics of monocyte-derived macrophage diversity in experimental myocardial infarction.
实验性心肌梗死中单核细胞衍生的巨噬细胞多样性的动力学。
Cardiovasc Res. 2023 May 2;119(3):772-785. doi: 10.1093/cvr/cvac113.
4
TIMP-1 expression in coronary thrombi associate with myocardial injury in ST-elevation myocardial infarction patients.TIMP-1 在 ST 段抬高型心肌梗死患者冠状动脉血栓中的表达与心肌损伤相关。
Coron Artery Dis. 2022 Sep 1;33(6):446-455. doi: 10.1097/MCA.0000000000001128. Epub 2022 Jan 31.
5
Interplay between inflammation and thrombosis in cardiovascular pathology.心血管病理学中的炎症与血栓形成的相互作用。
Nat Rev Cardiol. 2021 Sep;18(9):666-682. doi: 10.1038/s41569-021-00552-1. Epub 2021 May 6.
6
Role of perilipin 2 in microvascular obstruction in patients with ST-elevation myocardial infarction. perilipin 2 在 ST 段抬高型心肌梗死患者微血管阻塞中的作用。
Eur Heart J Acute Cardiovasc Care. 2021 Aug 24;10(6):633-642. doi: 10.1093/ehjacc/zuaa004.
7
Immunometabolism of Phagocytes and Relationships to Cardiac Repair.吞噬细胞的免疫代谢及其与心脏修复的关系
Front Cardiovasc Med. 2019 Apr 11;6:42. doi: 10.3389/fcvm.2019.00042. eCollection 2019.
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MIF-CD74 signaling impedes microglial M1 polarization and facilitates brain tumorigenesis.MIF-CD74 信号通路抑制小胶质细胞 M1 极化并促进脑肿瘤发生。
Oncogene. 2016 Dec 1;35(48):6246-6261. doi: 10.1038/onc.2016.160. Epub 2016 May 9.
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The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functions.正在愈合的心肌会依次动员两个具有不同且互补功能的单核细胞亚群。
J Exp Med. 2007 Nov 26;204(12):3037-47. doi: 10.1084/jem.20070885. Epub 2007 Nov 19.
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