Zapata Karina Amani, Nadolny Caitlin, Lovrich Eliza, Ma Yuhan, Ramo Brandon A
Scottish Rite for Children, 2222 Welborn Street, Dallas, TX, 75219, USA.
Texas Health Sports Medicine, Arlington, TX, USA.
Spine Deform. 2025 May;13(3):801-809. doi: 10.1007/s43390-024-01028-1. Epub 2025 Jan 13.
To compare health-related quality-of-life (HRQOL) between children with hyperkyphosis and idiopathic scoliosis using 9-item Oswestry Disability Index (ODI-9) and Patient Reported Outcome Measurement Information System (PROMIS) Pain Interference, Mobility, and Anxiety.
Children with hyperkyphosis, idiopathic scoliosis, and controls with no structural diagnosis ages 10-18 years who completed the PROMIS Pediatric Pain Interference, Mobility, and Anxiety domains were retrospectively evaluated from April 2021 to June 2023. Comparisons were made between hyperkyphosis, idiopathic scoliosis, and control groups. Within the hyperkyphosis group, comparisons were made between Scheuermann kyphosis and postural kyphosis subgroups.
304 children with hyperkyphosis, 1134 with idiopathic scoliosis, and 1493 controls were included. Children with hyperkyphosis had increased age, male sex, BMI percentile, Spanish than English speakers, and public insurance type. They also had worse ODI-9, PROMIS Pain Interference and Mobility scores which remained significant after multivariate regression analysis included age, sex, BMI percentile, language, insurance type, and race/ethnicity (p < 0.01). The Scheuermann kyphosis (n = 67) subgroup had increased age, male sex, area deprivation index (ADI), BMI percentile, concern by their appearance, and worse PROMIS Pain Interference and Mobility scores than the postural kyphosis (n = 237) subgroup. However, Scheuermann kyphosis subgroup score differences did not remain significant after considering age, sex, ADI, and BMI percentile.
Children with hyperkyphosis (both Scheuermann and postural kyphosis subtypes) have worse HRQOL scores than their peers with idiopathic scoliosis. Worse ODI-9, PROMIS Pain Interference and Mobility scores remained significant only in the hyperkyphosis group as a whole after adjusting for confounding variables, but not between hyperkyphosis subgroups.
使用9项奥斯威斯残疾指数（ODI-9）以及患者报告结局测量信息系统（PROMIS）的疼痛干扰、活动能力和焦虑量表，比较脊柱后凸过度儿童与特发性脊柱侧凸儿童的健康相关生活质量（HRQOL）。
对2021年4月至2023年6月期间完成PROMIS儿童疼痛干扰、活动能力和焦虑量表评估的10至18岁脊柱后凸过度儿童、特发性脊柱侧凸儿童以及无结构诊断的对照组儿童进行回顾性评估。对脊柱后凸过度组、特发性脊柱侧凸组和对照组进行比较。在脊柱后凸过度组中，对休曼氏脊柱后凸和姿势性脊柱后凸亚组进行比较。
纳入304例脊柱后凸过度儿童、1134例特发性脊柱侧凸儿童和1493例对照组儿童。脊柱后凸过度儿童年龄更大、男性居多、BMI百分位数更高、说西班牙语的比例高于说英语的、公共保险类型更多。他们的ODI-9、PROMIS疼痛干扰和活动能力得分也更低，在纳入年龄、性别、BMI百分位数、语言、保险类型和种族/族裔的多变量回归分析后，这些差异仍然显著（p < 0.01）。与姿势性脊柱后凸（n = 237）亚组相比，休曼氏脊柱后凸（n = 67）亚组年龄更大、男性居多、区域贫困指数（ADI）更高、BMI百分位数更高、更在意自己的外表，且PROMIS疼痛干扰和活动能力得分更差。然而，在考虑年龄、性别、ADI和BMI百分位数后，休曼氏脊柱后凸亚组的得分差异不再显著。
脊柱后凸过度儿童（包括休曼氏和姿势性脊柱后凸亚型）的HRQOL得分比同龄特发性脊柱侧凸儿童更差。在调整混杂变量后，较差的ODI-9、PROMIS疼痛干扰和活动能力得分仅在整个脊柱后凸过度组中仍然显著，但在脊柱后凸过度亚组之间并不显著。
