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2019年冠状病毒病疫情对英国高血压初级保健的影响:一项基于人群的队列研究。

Impact of the COVID-19 pandemic on primary care for hypertension in the UK: a population-based cohort study.

作者信息

Johnson Kyle, Beradid Sarah, Brophy James M, Platt Robert W, Renoux Christel

机构信息

Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, Québec, Canada.

Lady Davis Institute for Medical Research Centre for Clinical Epidemiology, Montreal, Québec, Canada.

出版信息

BMJ Open. 2024 Dec 20;14(12):e089834. doi: 10.1136/bmjopen-2024-089834.

DOI:10.1136/bmjopen-2024-089834
PMID:39806680
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11667485/
Abstract

OBJECTIVES

To describe the impact of the COVID-19 pandemic on hypertension diagnosis and management in UK primary care.

DESIGN

Population-based cohort study.

SETTING

Over 2000 general practices across the UK contributing to the Clinical Practice Research Datalink.

PARTICIPANTS

A cohort of 23 076 390 patients over 18 years of age and registered with their general practice for at least 1 year between 2011 and 2022, who did not have a previous diagnosis of hypertension. From these patients, a subcohort of 712 461 patients diagnosed with hypertension between 2011 and 2022 was selected.

PRIMARY AND SECONDARY OUTCOME MEASURES

Coprimary outcomes included rates of hypertension diagnosis and rates of antihypertensive treatment initiation, treatment change and blood pressure measurement in patients newly diagnosed with hypertension.

RESULTS

In April 2020, the first month of lockdown, incident hypertension diagnosis rates fell by 65% (95% CI 64% to 67%) compared with historical trends and remained depressed until November 2021, leading to 51 000 fewer diagnoses than expected by March 2022. However, by March 2022, there were 2.6% fewer diagnoses than expected in Scotland, compared with 20%-30% fewer in other UK Nations. Rates of treatment initiation and change fell by 47% (95% CI 43% to 51%) and 36% (95% CI 33% to 38%), respectively, in April 2020. However, initiation rates rebounded above expectations and remained elevated until March 2022. Blood pressure measurements fell by 69% (95% CI 65% to 72%) in April 2020, recovering in February 2021.

CONCLUSIONS

Hypertension diagnosis and management in UK primary care were significantly disrupted during the COVID-19 pandemic. Future studies should investigate the potential clinical implications for the cardiovascular health of the UK population.

摘要

目的

描述2019冠状病毒病(COVID-19)大流行对英国初级医疗中高血压诊断和管理的影响。

设计

基于人群的队列研究。

背景

英国2000多家参与临床实践研究数据链的全科诊所。

参与者

23076390名18岁以上的患者队列,他们在2011年至2022年期间在全科诊所注册至少1年,且此前未被诊断为高血压。从这些患者中,选取了712461名在2011年至2022年期间被诊断为高血压的患者亚组。

主要和次要结局指标

共同主要结局包括新诊断高血压患者的高血压诊断率、抗高血压治疗起始率、治疗改变率和血压测量率。

结果

2020年4月,封锁的第一个月,与历史趋势相比,新发高血压诊断率下降了65%(95%置信区间64%至67%),并一直低迷至2021年11月,到2022年3月导致比预期少51000例诊断。然而,到2022年3月,苏格兰的诊断比预期少2.6%,而英国其他地区则少20%-30%。2020年4月,治疗起始率和治疗改变率分别下降了47%(95%置信区间43%至51%)和36%(95%置信区间33%至38%)。然而,起始率反弹至预期之上,并一直居高不下至2022年3月。2020年4月血压测量下降了69%(95%置信区间65%至72%),2021年2月恢复。

结论

COVID-19大流行期间,英国初级医疗中的高血压诊断和管理受到显著干扰。未来的研究应调查对英国人群心血管健康的潜在临床影响。

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