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表现为局部晚期甲状腺癌的气管腺样囊性癌。

Tracheal adenoid cystic carcinoma presenting as a locally advanced thyroid gland carcinoma.

作者信息

Ayed Mariam Ben, Tbini Makram, Riahi Inès, Idriss Sarra, Salah Mamia Ben

机构信息

Department of Otorhinolaryngology Head and Neck Surgery, Charles Nicolle Hospital, Tunis, Tunisia.

Faculty of Medicine, University Tunis el Manar, Tunis, Tunisia.

出版信息

Radiol Case Rep. 2024 Dec 19;20(3):1406-1409. doi: 10.1016/j.radcr.2024.11.058. eCollection 2025 Mar.

DOI:10.1016/j.radcr.2024.11.058
PMID:39807115
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11728663/
Abstract

Tracheal adenoid cystic carcinoma is a rare malignancy. We report the case of a 65-year-old male who presented to our department due to a 3-month history of mild dysphagia without other associated symptoms. The neck, laryngeal, and hypopharyngeal examinations were normal. Ultrasound showed hypertrophy and marked hypoechogenicity of the left thyroid lobe without suspicious nodules. Fine needle aspiration of the hypoechogenic area revealed an adenoid cystic carcinoma. A tracheal origin was then suspected and it was confirmed by a flexible bronchoscopy that showed a tumor located in the proximal tracheal reducing its lumen by 50%. The biopsy confirmed the diagnosis of tracheal adenoid cystic carcinoma. We performed a computed tomography scan showing a mass at the angle between the trachea and esophagus infiltrating the left thyroid gland. Magnetic resonance imaging confirmed the tumor's important local and regionregional extension at the thyroid gland, esophagus, larynx, and mediastinum. The tumor was judged as unresectable and the patient received radiotherapy and an endotracheal sent. After a follow-up period of 2 years, the tumor remained stable, and the patient received This study aims to determine the clinical, radiological, and therapeutic aspects of advanced adenoid cystic carcinoma.

摘要

气管腺样囊性癌是一种罕见的恶性肿瘤。我们报告一例65岁男性患者,因3个月的轻度吞咽困难病史前来我院就诊,无其他相关症状。颈部、喉部和下咽检查均正常。超声显示左甲状腺叶肥大且回声明显减低,无可疑结节。对低回声区进行细针穿刺活检,结果显示为腺样囊性癌。随后怀疑肿瘤起源于气管,经柔性支气管镜检查证实,肿瘤位于气管近端,使管腔缩小50%。活检确诊为气管腺样囊性癌。我们进行了计算机断层扫描,显示气管与食管夹角处有一肿块,侵犯左侧甲状腺。磁共振成像证实肿瘤在甲状腺、食管、喉部和纵隔有重要的局部和区域扩展。该肿瘤被判定为不可切除,患者接受了放疗和气管支架置入。经过2年的随访,肿瘤保持稳定,患者接受了……本研究旨在确定晚期腺样囊性癌的临床、影像学和治疗方面的情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de34/11728663/044b4f8b6447/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de34/11728663/218f754e70d5/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de34/11728663/356b7fb2d995/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de34/11728663/8066c3ae0c92/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de34/11728663/044b4f8b6447/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de34/11728663/218f754e70d5/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de34/11728663/356b7fb2d995/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de34/11728663/8066c3ae0c92/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de34/11728663/044b4f8b6447/gr4.jpg

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本文引用的文献

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Primary trachea adenoid cystic carcinoma invading the thyroid gland: A case report.
Asian J Surg. 2024 Mar;47(3):1585-1586. doi: 10.1016/j.asjsur.2023.12.022. Epub 2023 Dec 15.
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Adenoid cystic carcinoma of the trachea mimicking asthma.酷似哮喘的气管腺样囊性癌
Respirol Case Rep. 2023 Apr 20;11(5):e01148. doi: 10.1002/rcr2.1148. eCollection 2023 May.
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Expanding role of radiotherapy in adenoid cystic carcinoma of the tracheobronchial tree: a new horizon.扩大放射治疗在气管支气管腺样囊性癌中的作用:新的视野。
Tumori. 2022 Aug;108(4):347-356. doi: 10.1177/03008916211012461. Epub 2021 May 12.
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Patterns of Care and Outcomes of Primary Adenoid Cystic Carcinoma of the Trachea.气管原发性腺样囊性癌的治疗模式和结局。
Ann Otol Rhinol Laryngol. 2022 Jan;131(1):78-85. doi: 10.1177/00034894211008101. Epub 2021 Apr 19.
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Primary adenoid cystic carcinoma of the lung: A case report and literature review.原发性肺腺样囊性癌:一例报告并文献复习
Heliyon. 2021 Feb 5;7(2):e06206. doi: 10.1016/j.heliyon.2021.e06206. eCollection 2021 Feb.
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Adenoid Cystic Carcinoma of the Trachea: A Case Report.气管腺样囊性癌:一例报告
Am J Case Rep. 2019 Sep 17;20:1373-1377. doi: 10.12659/AJCR.917136.
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Primary adenoid cystic carcinoma of the trachea: clinical outcome of 38 patients after interdisciplinary treatment in a single institution.气管原发性腺样囊性癌:单中心多学科治疗 38 例患者的临床结局。
Radiat Oncol. 2019 Jul 4;14(1):117. doi: 10.1186/s13014-019-1323-z.
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