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呼吸道合胞病毒(RSV)诱发的以晕厥为表现的自身免疫性溶血性贫血:一例报告

Respiratory Syncytial Virus (RSV)-Induced Autoimmune Hemolytic Anemia Presenting as Syncope: A Case Report.

作者信息

Johns James T

机构信息

Emergency Medicine, University Hospitals St. John Medical Center, Westlake, USA.

出版信息

Cureus. 2025 Jan 13;17(1):e77369. doi: 10.7759/cureus.77369. eCollection 2025 Jan.

Abstract

Autoimmune hemolytic anemia (AIHA) is a condition that causes an individual's immune system to destroy its own red blood cells. Immune cells are activated against the red blood cell antigens to induce hemolysis. Patients typically present with symptomatic anemia when the extent of hemolysis overcomes the bone marrow's ability to compensate. Steroids are typically the first-line treatment, along with supportive care and blood transfusion for severe anemia. This case report details a patient who had presented to the ED after a syncopal episode that was ultimately due to respiratory syncytial virus (RSV)-induced warm AIHA.

摘要

自身免疫性溶血性贫血(AIHA)是一种导致个体免疫系统破坏自身红细胞的病症。免疫细胞针对红细胞抗原被激活,从而引发溶血。当溶血程度超过骨髓的代偿能力时,患者通常会出现症状性贫血。类固醇通常是一线治疗药物,同时还包括支持性护理以及针对严重贫血的输血治疗。本病例报告详细介绍了一名患者,该患者在一次晕厥发作后被送往急诊科,最终诊断为呼吸道合胞病毒(RSV)诱发的温抗体型自身免疫性溶血性贫血。

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Autoimmune Hemolytic Anemia: Diagnosis and Differential Diagnosis.自身免疫性溶血性贫血:诊断与鉴别诊断。
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How I treat warm autoimmune hemolytic anemia.我如何治疗温抗体自身免疫性溶血性贫血。
Blood. 2021 Mar 11;137(10):1283-1294. doi: 10.1182/blood.2019003808.
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Autoimmune hemolytic anemia.自身免疫性溶血性贫血。
Hematology Am Soc Hematol Educ Program. 2018 Nov 30;2018(1):382-389. doi: 10.1182/asheducation-2018.1.382.
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Paroxysmal cold hemoglobinuria in a child with RSV: an underrecognized cause of hemolytic anemia.
Am J Emerg Med. 2016 Nov;34(11):2252.e5-2252.e6. doi: 10.1016/j.ajem.2016.04.034. Epub 2016 Apr 23.
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A practical approach to investigation of syncope.晕厥的实用调查方法。
Can J Cardiol. 2014 Jun;30(6):671-4. doi: 10.1016/j.cjca.2014.03.043. Epub 2014 Apr 3.
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