• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

人乳乳清蛋白:成分、影响因素、检测方法以及与其他来源的比较分析

Human milk whey proteins: Constituents, influencing factors, detection methods, and comparative analysis with other sources.

作者信息

Li Xing, Zhang Xiaomei, Zhang Minghui, Liu Xiaojia, Gao Ziyue, Zhao Junying, Qiao Weicang, Chen Lijun

机构信息

Key Laboratory of Dairy Science, Ministry of Education, Food Science College, Northeast Agricultural University, Harbin, 150030, China.

National Engineering Research Center of Dairy Health for Maternal and Child, Beijing Sanyuan Foods Co. Ltd., Beijing 100163, China.

出版信息

Food Chem X. 2024 Dec 9;25:102082. doi: 10.1016/j.fochx.2024.102082. eCollection 2025 Jan.

DOI:10.1016/j.fochx.2024.102082
PMID:39807410
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11729002/
Abstract

Whey proteins, the most abundant proteins in human milk (HM), play a vital role in the growth and development of infants. This review first elaborates on the main components of HM whey proteins, including various proteins with specific functions, and details the functions of these proteins in terms of infant nutrition, immunity, as well as growth and development. Secondly, it analyzes factors that affect HM whey proteins, such as maternal differences, dietary habits, and geographical differences. Thirdly, it discusses detection methods for HM whey proteins, covering the principles, advantages, and limitations of different technical means. Finally, it compares whey proteins from different milk sources, highlighting their differences in composition, function, and characteristics. This review aims to comprehensively present the current research status of HM whey protein, provide a scientific basis for maternal and infant health, and contribute to optimizing infant feeding strategies and the research and development of related products.

摘要

乳清蛋白是母乳(HM)中最丰富的蛋白质,对婴儿的生长发育起着至关重要的作用。本综述首先阐述了母乳乳清蛋白的主要成分,包括具有特定功能的各种蛋白质,并详细说明了这些蛋白质在婴儿营养、免疫以及生长发育方面的功能。其次,分析了影响母乳乳清蛋白的因素,如母亲差异、饮食习惯和地域差异。第三,讨论了母乳乳清蛋白的检测方法,涵盖了不同技术手段的原理、优点和局限性。最后,比较了不同奶源的乳清蛋白,突出了它们在组成、功能和特性上的差异。本综述旨在全面呈现母乳乳清蛋白的当前研究现状,为母婴健康提供科学依据,并有助于优化婴儿喂养策略以及相关产品的研发。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eff9/11729002/262f5adc61ec/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eff9/11729002/83e785c2c1c1/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eff9/11729002/48254320d37a/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eff9/11729002/262f5adc61ec/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eff9/11729002/83e785c2c1c1/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eff9/11729002/48254320d37a/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eff9/11729002/262f5adc61ec/gr3.jpg

相似文献

1
Human milk whey proteins: Constituents, influencing factors, detection methods, and comparative analysis with other sources.人乳乳清蛋白:成分、影响因素、检测方法以及与其他来源的比较分析
Food Chem X. 2024 Dec 9;25:102082. doi: 10.1016/j.fochx.2024.102082. eCollection 2025 Jan.
2
Comparative Analysis of Whey Proteins in Human Milk Using a Data-Independent Acquisition Proteomics Approach during the Lactation Period.哺乳期人乳乳清蛋白的非依赖性数据获取蛋白质组学分析比较。
J Agric Food Chem. 2021 Apr 14;69(14):4319-4330. doi: 10.1021/acs.jafc.1c00186. Epub 2021 Mar 31.
3
Human Milk Proteins: Composition and Physiological Significance.人乳蛋白质:组成与生理意义
Nestle Nutr Inst Workshop Ser. 2019;90:93-101. doi: 10.1159/000490298. Epub 2019 Mar 13.
4
Growth promotion of Bifidobacterium species by whey and casein fractions from human and bovine milk.人乳和牛乳中的乳清及酪蛋白成分对双歧杆菌属的生长促进作用。
J Clin Microbiol. 1990 Feb;28(2):287-92. doi: 10.1128/jcm.28.2.287-292.1990.
5
Comparative Whey Proteome Profiling of Donkey Milk With Human and Cow Milk.驴奶与人奶和牛奶的乳清蛋白质组比较分析
Front Nutr. 2022 Jun 27;9:911454. doi: 10.3389/fnut.2022.911454. eCollection 2022.
6
"OMICS" in Human Milk: Focus on Biological Effects on Bone Homeostasis.人乳中的“组学”:关注对骨稳态的生物学效应。
Nutrients. 2024 Nov 17;16(22):3921. doi: 10.3390/nu16223921.
7
Human Milk Casein and Whey Protein and Infant Body Composition over the First 12 Months of Lactation.人乳酪蛋白和乳清蛋白与婴儿在哺乳期第 12 个月的身体成分。
Nutrients. 2018 Sep 19;10(9):1332. doi: 10.3390/nu10091332.
8
Longitudinal Analysis of Macronutrient Composition in Preterm and Term Human Milk: A Prospective Cohort Study.早产儿和足月母乳宏量营养素成分的纵向分析:一项前瞻性队列研究。
Nutrients. 2019 Jul 4;11(7):1525. doi: 10.3390/nu11071525.
9
Comparative proteomic exploration of whey proteins in human and bovine colostrum and mature milk using iTRAQ-coupled LC-MS/MS.使用iTRAQ偶联液相色谱-串联质谱法对人初乳、牛初乳及成熟乳中的乳清蛋白进行比较蛋白质组学研究。
Int J Food Sci Nutr. 2017 Sep;68(6):671-681. doi: 10.1080/09637486.2017.1279129. Epub 2017 Feb 20.
10
Comparative Proteomics of Whey and Milk Fat Globule Membrane Proteins of Guanzhong Goat and Holstein Cow Mature Milk.乳清蛋白和关中奶山羊及荷斯坦牛乳脂肪球膜蛋白成熟乳的比较蛋白质组学研究。
J Food Sci. 2019 Feb;84(2):244-253. doi: 10.1111/1750-3841.14428. Epub 2019 Jan 8.

引用本文的文献

1
Breastfeeding: The Multifaceted Impact on Child Development and Maternal Well-Being.母乳喂养:对儿童发育和母亲福祉的多方面影响。
Nutrients. 2025 Apr 11;17(8):1326. doi: 10.3390/nu17081326.
2
Challenges and Opportunities in Quantifying Bioactive Compounds in Human Breastmilk.定量分析人乳中生物活性化合物的挑战与机遇
Biomolecules. 2025 Feb 24;15(3):325. doi: 10.3390/biom15030325.

本文引用的文献

1
Difference in Allergenicity between β-Lactoglobulin in Bovine Milk and Caprine Milk is Related to Their Respective Digestive Stability.牛乳β-乳球蛋白和山羊乳β-乳球蛋白的变应原性差异与其各自的消化稳定性有关。
J Agric Food Chem. 2024 Oct 30;72(43):23969-23978. doi: 10.1021/acs.jafc.4c05954. Epub 2024 Oct 17.
2
The Effect of Ultrasound Treatment on the Structural and Functional Properties of Myofibrillar Protein.超声处理对肌原纤维蛋白结构和功能特性的影响
Foods. 2024 Sep 5;13(17):2817. doi: 10.3390/foods13172817.
3
The Concentration of Lactoferrin in Breast Milk Correlates with Maternal Body Mass Index and Parity.
母乳中乳铁蛋白的浓度与母体体重指数和产次相关。
Breastfeed Med. 2024 Mar;19(3):208-216. doi: 10.1089/bfm.2023.0215.
4
Reduction in the antigenicity of beta-lactoglobulin in whole milk powder via supercritical CO treatment.通过超临界CO₂处理降低全脂奶粉中β-乳球蛋白的抗原性。
J Dairy Sci. 2024 Jul;107(7):4216-4234. doi: 10.3168/jds.2023-24565. Epub 2024 Mar 8.
5
Maternal milk in the NICU: An everyday intervention to improve brain development.新生儿重症监护病房中的母乳:改善大脑发育的日常干预措施。
Pediatr Res. 2024 Jul;96(1):27-29. doi: 10.1038/s41390-024-03125-3. Epub 2024 Mar 4.
6
Lysozyme: A Natural Product with Multiple and Useful Antiviral Properties.溶菌酶:一种具有多种有用抗病毒特性的天然产物。
Molecules. 2024 Jan 30;29(3):652. doi: 10.3390/molecules29030652.
7
Digestive properties and peptide profiles exhibited significant differences between skim camel milk and bovine milk powder after static in vitro simulated infant gastrointestinal digestion.在静态体外模拟婴儿胃肠道消化后,脱脂骆驼奶和牛奶粉的消化特性和肽谱表现出显著差异。
Food Res Int. 2024 Feb;178:113860. doi: 10.1016/j.foodres.2023.113860. Epub 2023 Dec 16.
8
Fabrication of dry S/O/W microcapsule and its probiotic protection against different stresses.干型水包油包固体微胶囊的制备及其对益生菌的不同应激保护作用。
J Sci Food Agric. 2024 Mar 30;104(5):2842-2850. doi: 10.1002/jsfa.13175. Epub 2023 Dec 9.
9
Synergistic effect of lactoferrin and osteopontin on intestinal barrier injury.乳铁蛋白和骨桥蛋白对肠道屏障损伤的协同作用。
Int J Biol Macromol. 2023 Dec 31;253(Pt 7):127416. doi: 10.1016/j.ijbiomac.2023.127416. Epub 2023 Oct 13.
10
Comparative Analysis of Protein Digestion Characteristics in Human, Cow, Goat, Sheep, Mare, and Camel Milk under Simulated Infant Condition.模拟婴幼儿条件下人乳、牛乳、羊乳、山羊乳、马乳和驼乳中蛋白质消化特性的比较分析。
J Agric Food Chem. 2023 Oct 18;71(41):15035-15047. doi: 10.1021/acs.jafc.3c03123. Epub 2023 Oct 6.