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抗生素使用与抗菌药物耐药性:对医学生进行知识、态度和实践调查以评估本科培训课程

Antibiotic use and antimicrobial resistance: Knowledge, Attitude and Practices survey of medical students to evaluate undergraduate training curriculum.

作者信息

Saksena Rushika, Parida Annapurna, Jain Madhura, Gaind Rajni

机构信息

Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.

出版信息

Access Microbiol. 2025 Jan 8;7(1). doi: 10.1099/acmi.0.000638.v4. eCollection 2025.

Abstract

A better understanding of knowledge, attitude and practices of undergraduate medical students towards antimicrobial resistance (AMR) is necessary to identify gaps in the current training curriculum. A 20-point Likert scale-based questionnaire divided into three parts, knowledge, attitude and practices, relating to antibiotic use and resistance was devised. Students attending each year of the undergraduate medical programme were approached to participate in the study over a 1-week period. Knowledge, Attitude and Practices scores of each year were compared through logistic ordinal regression and the Kruskal-Wallis (KW) test. Two hundred and eight students participated in the study. Overall, knowledge of about intended use of antibiotics, fixed drug combinations and awareness about AMR was good (average score of 73.75%). Steady improvement in knowledge scores was observed from the first year (-0.441) to the final year (0.00). The medical students had favourable attitude towards rational antimicrobial use (Likert score ≥4), including the need to spread awareness about AMR amongst students and the public and following doctor's prescriptions. Self-medication was reported by 28.4% of students and hoarding of leftover doses by 49.1%. Attitude score had a direct correlation with the knowledge score on the KW test ( =29.6, ≤0.5) but had no significant correlation with antimicrobial practices ( =3.9, ≥0.5). The gaps identified in students' practices included self-medication, skipping of dosing and hoarding of leftover medication. As improvement in knowledge did not correlate with better personal behaviours regarding antibiotics, the current curriculum needs to include AMR as a focus area to ensure good antibiotic prescribing practices in future practitioners.

摘要

为了找出当前培训课程中的差距,有必要更好地了解本科医学生对抗菌药物耐药性(AMR)的知识、态度和行为。设计了一份基于20分李克特量表的问卷,分为与抗生素使用和耐药性相关的三个部分:知识、态度和行为。在为期1周的时间里,邀请了本科医学课程各年级的学生参与这项研究。通过逻辑序数回归和Kruskal-Wallis(KW)检验比较了各年级的知识、态度和行为得分。共有208名学生参与了这项研究。总体而言,学生对预期的抗生素使用、固定药物组合以及对抗菌药物耐药性的认识良好(平均得分73.75%)。从第一年(-0.441)到最后一年(0.00),知识得分呈稳步提高。医学生对合理使用抗菌药物持积极态度(李克特得分≥4),包括需要在学生和公众中传播对抗菌药物耐药性的认识以及遵循医生的处方。28.4%的学生报告有自我用药情况,49.1%的学生报告有囤积剩余剂量的情况。在KW检验中,态度得分与知识得分直接相关(=29.6,≤0.5),但与抗菌药物使用行为无显著相关性(=3.9,≥0.5)。学生在行为方面发现的差距包括自我用药、漏服剂量和囤积剩余药物。由于知识的提高与更好的抗生素个人使用行为不相关,当前课程需要将抗菌药物耐药性作为一个重点领域,以确保未来从业者有良好的抗生素处方习惯。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cd8/11725644/993637fde1c4/acmi-7-00638-g001.jpg

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