儿童中与局限性脉络膜凹陷（FCE）相关的脉络膜新生血管膜（CNV）
Focal choroidal excavation (FCE)-related choroidal neovascular membrane (CNV) in a child.
作者信息
McDonald Jacinta A, Barkmeier Andrew J, Dalvin Lauren A, Scruggs Brittni A
机构信息
Mayo Clinic Alix School of Medicine, Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905.
Department of Ophthalmology, Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905.
出版信息
Retin Cases Brief Rep. 2024 Jun 11;19(4):507-12. doi: 10.1097/ICB.0000000000001597.
PURPOSE
To report the rare clinical, optical coherence tomography (OCT), and OCT-angiography findings of a visually significant choroidal neovascular membrane (CNV) in the setting of focal choroidal excavation (FCE) in a child.
METHODS
Case report and literature review.
RESULTS
A 9-year-old girl with FCE-related central CNV based on clinical findings and multimodal imaging. Patient's visual acuity and retinal findings progressed, and she started bevacizumab intravitreal therapy (off label) with resultant stepwise improvement of visual acuity and retinal imaging findings, including regression of a neovascular complex on OCT-A.
CONCLUSION
This case highlights the successful use of bevacizumab for a rare choroidal neovascular complex associated with FCE in a child.
目的
报告一名儿童在局灶性脉络膜凹陷（FCE）情况下出现具有明显视力影响的脉络膜新生血管膜（CNV）的罕见临床、光学相干断层扫描（OCT）及OCT血管造影表现。
方法
病例报告及文献复习。
结果
一名9岁女孩，基于临床检查结果及多模态成像诊断为与FCE相关的中心性CNV。患者的视力及视网膜表现有所进展，遂开始玻璃体内注射贝伐单抗（未按说明书用药）治疗，视力及视网膜成像表现逐步改善，包括OCT血管造影显示新生血管复合体消退。
结论
该病例突出了贝伐单抗成功用于治疗一名儿童罕见的与FCE相关的脉络膜新生血管复合体。
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