Bragança Francisca, Menéres Pedro, Furtado Maria João, Pessoa Bernardete
Department of Ophthalmology, Unidade Local de Saúde de Santo António, Oporto, Portugal.
Department of Ophthalmology, Unidade Local de Saúde de Santo António, Oporto, Portugal; Institute for the Biomedical Sciences Abel Salazar - University of Porto, (UMIB ICBAS - UP), Oporto, Portugal.
J AAPOS. 2025 Jun;29(3):104204. doi: 10.1016/j.jaapos.2025.104204. Epub 2025 Apr 12.
A 13-year-old girl presented with a complaint of left eye central scotoma. Past medical history was unremarkable, and there were no associated systemic symptoms. Best-corrected visual acuity was 10/10 in the right eye (-2.00 -1.75 ×100°) and 1/10 in the left eye (-1.50 -2.25 ×80°). Macular spectral domain optical coherence tomography (SD-OCT) revealed subretinal and sub-retinal pigment epithelium hyperreflective material in the left eye with associated subretinal fluid, involving the foveal area, suggestive of an extrafoveal mixed type macular neovascularization (MNV), further evidenced through OCT angiography and fluorescein angiography. A focal choroidal excavation (FCE) was associated with this MNV. Thorough systemic investigation retrieved no abnormalities. A diagnosis of secondary FCE-related MNV was made. Treatment was initiated with anti-vascular endothelial growth factor intravitreal injections, with a total of 6 injections in a treat-and-extend regimen up to the most recent follow-up visit, 10 months after presentation. During follow-up, functional and structural improvement was observed, and there were no signs of recurrence of exudation.
一名13岁女孩因左眼中心暗点就诊。既往病史无异常,也无相关全身症状。右眼最佳矫正视力为10/10(-2.00 -1.75 ×100°),左眼为1/10(-1.50 -2.25 ×80°)。黄斑区光谱域光学相干断层扫描(SD-OCT)显示左眼视网膜下及视网膜色素上皮下高反射物质,并伴有视网膜下液,累及黄斑中心凹区域,提示为黄斑中心凹外混合型黄斑新生血管(MNV),光学相干断层扫描血管造影和荧光素血管造影进一步证实了这一点。一个局限性脉络膜凹陷(FCE)与该MNV相关。全面的系统检查未发现异常。诊断为继发性FCE相关MNV。开始采用抗血管内皮生长因子玻璃体内注射治疗,在治疗并延长方案中总共注射了6次,直至就诊后10个月的最近一次随访。随访期间,观察到功能和结构有所改善,且无渗出复发迹象。