Therre Markus, Tokcan Mert, Markwirth Philipp, Böhm Michael
Klinik für Kardiologie, Angiologie und internistische Intensivmedizin, Universitätsklinikum des Saarlandes, Kirrberger Str. 1, 66421, Homburg/Saar, Deutschland.
Herz. 2025 Apr;50(2):149-158. doi: 10.1007/s00059-024-05291-w. Epub 2025 Jan 14.
Respiratory tract infections with influenza, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and respiratory syncytial (RS) viruses and pneumococci as well as endogenous reactivation of varicella zoster viruses presenting as herpes zoster, are associated with adverse cardiovascular outcomes, such as myocardial infarction or hospitalization for heart failure. Effective prevention of these events, particularly through influenza and pneumococcal vaccination, is well established and cost-effective. Despite guideline recommendations to vaccinate older patients and people at risk, vaccination rates in these population groups remain suboptimal and below average in international comparison. This article sheds light on the association of vaccine preventable diseases with cardiovascular complications and demonstrates the protective effect of the respective vaccinations. Additionally, recommendations on the practical approach to vaccinating high-risk patients are given.
流感、严重急性呼吸综合征冠状病毒2(SARS-CoV-2)、呼吸道合胞(RS)病毒和肺炎球菌引起的呼吸道感染,以及表现为带状疱疹的水痘带状疱疹病毒的内源性再激活,均与不良心血管结局相关,如心肌梗死或因心力衰竭住院。有效预防这些事件,特别是通过流感和肺炎球菌疫苗接种,已得到充分证实且具有成本效益。尽管有指南建议对老年患者和高危人群进行疫苗接种,但在国际比较中,这些人群的疫苗接种率仍不理想且低于平均水平。本文阐明了疫苗可预防疾病与心血管并发症之间的关联,并展示了相应疫苗接种的保护作用。此外,还给出了针对高危患者进行疫苗接种的实际方法建议。