Hollander D I, Halwig J M, McKinney P, Patterson R
J Allergy Clin Immunol. 1985 Apr;75(4):450-1. doi: 10.1016/s0091-6749(85)80016-6.
Elephantiasis nostras is a rare condition that usually presents as a persistent swelling of the lower extremity secondary to recurrent lymphangitis. We present a patient, originally referred for "angioneurotic edema of the lip," who presented with a history of several months of persistent swelling of the upper lip. There was probable evidence for recent infection of the lip that is consistent with the diagnosis of elephantiasis nostras. This disease should be included in the differential diagnosis of chronic persistent angioedema of the lip.
