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子宫内膜异位症诊断与管理的进展:全面综述

Advances in the diagnosis and management of endometriosis: A comprehensive review.

作者信息

Chen Yingying, Waseem Shanza, Luo Li

机构信息

Department of Obstetrics and Gynecology, West China Second University Hospital, Sichuan University, Chengdu, China; Key Laboratory of Birth Defects and Related Diseases of Women and Children, Sichuan University, Ministry of Education, Chengdu, China.

Department of Obstetrics and Gynecology, West China Second University Hospital, Sichuan University, Chengdu, China; Department of Gynecology and Obstetrics, Key Laboratory of Birth Defects and Related Diseases of Women and Children of MOE, West China Second Hospital, Sichuan University, Chengdu, Sichuan Province 610041, China.

出版信息

Pathol Res Pract. 2025 Feb;266:155813. doi: 10.1016/j.prp.2025.155813. Epub 2025 Jan 9.

DOI:10.1016/j.prp.2025.155813
PMID:39808858
Abstract

Endometriosis is a prevalent gynecological condition characterized by the presence of endometrial-like tissue outside the uterus, leading to chronic pelvic pain and infertility. This review aims to shed light on the latest advancements in diagnosing and managing endometriosis. It offers insight into the condition's pathogenesis, clinical symptoms, diagnostic techniques, and available treatment approaches. Furthermore, the article emphasizes innovative technologies and novel therapeutic strategies that promise to enhance patient outcomes significantly. This review aspires to empower clinicians to deliver the highest quality care to their patients affected by this challenging condition by consolidating the current understanding of endometriosis.

摘要

子宫内膜异位症是一种常见的妇科疾病,其特征是子宫外存在类似子宫内膜的组织,导致慢性盆腔疼痛和不孕。本综述旨在阐明子宫内膜异位症诊断和管理方面的最新进展。它深入探讨了该疾病的发病机制、临床症状、诊断技术和可用的治疗方法。此外,文章强调了有望显著改善患者治疗效果的创新技术和新型治疗策略。本综述旨在通过巩固目前对子宫内膜异位症的认识,使临床医生能够为受这一具有挑战性疾病影响的患者提供最高质量的护理。

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1
Advances in the diagnosis and management of endometriosis: A comprehensive review.子宫内膜异位症诊断与管理的进展:全面综述
Pathol Res Pract. 2025 Feb;266:155813. doi: 10.1016/j.prp.2025.155813. Epub 2025 Jan 9.
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The connection between endometriosis and secondary dysmenorrhea.子宫内膜异位症与继发性痛经之间的联系。
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Management of the pain associated with endometriosis: an update of the painful problems.子宫内膜异位症相关疼痛的管理:疼痛问题的最新进展
Tohoku J Exp Med. 2006 Nov;210(3):175-88. doi: 10.1620/tjem.210.175.
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Endometriosis: current management.子宫内膜异位症:当前的治疗方法
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J Clin Med. 2025 Mar 12;14(6):1904. doi: 10.3390/jcm14061904.
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Cell. 2021 May 27;184(11):2807-2824. doi: 10.1016/j.cell.2021.04.041.
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Management of women with endometriosis in the 21st century.21世纪子宫内膜异位症女性的管理
Curr Opin Obstet Gynecol. 2025 Jun 1;37(3):149-157. doi: 10.1097/GCO.0000000000001027. Epub 2025 Apr 10.
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Short review on adverse childhood experiences, pelvic pain and endometriosis.关于不良儿童经历、盆腔痛和子宫内膜异位症的简要综述。
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引用本文的文献

1
Identification of Candidate Genes for Endometriosis in a Three-Generation Family with Multiple Affected Members Using Whole-Exome Sequencing.利用全外显子组测序在一个有多名患病成员的三代家族中鉴定子宫内膜异位症的候选基因
Biomedicines. 2025 Aug 6;13(8):1922. doi: 10.3390/biomedicines13081922.
2
Expression of Toll-like Receptors on Lymphocyte Subpopulations and Their Soluble Forms in Serum and Urine of Women with Endometriosis.子宫内膜异位症女性血清和尿液中淋巴细胞亚群上Toll样受体及其可溶性形式的表达
Cells. 2025 Aug 18;14(16):1273. doi: 10.3390/cells14161273.
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Cytokine profiles and metabolic dysregulation in endometriosis: insights into diagnostic and therapeutic targets.
子宫内膜异位症中的细胞因子谱与代谢失调:对诊断和治疗靶点的见解
Mol Biol Rep. 2025 Jun 26;52(1):641. doi: 10.1007/s11033-025-10766-y.