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Retraction Note: LRPPRC regulates malignant behaviors, protects mitochondrial homeostasis, mitochondrial function in osteosarcoma and derived cancer stem-like cells.撤稿说明:LRPPRC调节骨肉瘤及衍生的癌干细胞样细胞的恶性行为,保护线粒体稳态和线粒体功能。
BMC Cancer. 2025 Jan 14;25(1):79. doi: 10.1186/s12885-025-13492-7.
2
LRPPRC regulates malignant behaviors, protects mitochondrial homeostasis, mitochondrial function in osteosarcoma and derived cancer stem-like cells.LRPPRC 调节恶性行为,保护骨肉瘤和衍生的癌干样细胞中线粒体的内稳态和线粒体功能。
BMC Cancer. 2023 Oct 3;23(1):935. doi: 10.1186/s12885-023-11443-8.
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The Identification of a Key Regulator of Mitochondrial Metabolism, the LRPPRC Protein, as a Novel Therapeutic Target in SDHA-Overexpressing Ovarian Tumors.线粒体代谢关键调节因子LRPPRC蛋白被鉴定为SDHA过表达卵巢肿瘤的新型治疗靶点。
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The Biological Role of LRPPRC in Human Cancers.LRPPRC在人类癌症中的生物学作用
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Mitochondrial-Associated Protein LRPPRC is Related With Poor Prognosis Potentially and Exerts as an Oncogene Maintaining Mitochondrial Function in Pancreatic Cancer.线粒体相关蛋白LRPPRC可能与胰腺癌的不良预后相关,并作为一种癌基因发挥作用,维持胰腺癌的线粒体功能。
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Gossypol acetic acid regulates leukemia stem cells by degrading LRPPRC inhibiting IL-6/JAK1/STAT3 signaling or resulting mitochondrial dysfunction.醋酸棉酚通过降解LRPPRC、抑制IL-6/JAK1/STAT3信号传导或导致线粒体功能障碍来调节白血病干细胞。
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Disruption of affects B cell development and proliferation in a mouse model of Leigh Syndrome French Canadian type.在法裔加拿大人型Leigh综合征小鼠模型中,[此处缺失具体内容]的破坏会影响B细胞的发育和增殖。
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Leucyl-tRNA synthetase promotes malignant progression in diffuse large B-cell lymphoma by regulating glycolysis via the LRPPRC/HIF-1α/HK2 axis.亮氨酰-tRNA合成酶通过LRPPRC/HIF-1α/HK2轴调节糖酵解促进弥漫性大B细胞淋巴瘤的恶性进展。
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本文引用的文献

1
Retracted: N-myc Downstream-Regulated Gene 1 (NDRG1) Regulates Vascular Endothelial Growth Factor A (VEGFA) and Malignancies in Glioblastoma Multiforme (GBM).撤回:N- myc下游调控基因1(NDRG1)调节多形性胶质母细胞瘤(GBM)中的血管内皮生长因子A(VEGFA)和恶性肿瘤。
Biomed Res Int. 2023 Oct 4;2023:9794063. doi: 10.1155/2023/9794063. eCollection 2023.
2
Chelerythrine Inhibits Stemness of Cancer Stem-Like Cells of Osteosarcoma and PI3K/AKT/mTOR Signal.白屈菜红碱抑制骨肉瘤癌干细胞样细胞的干性及PI3K/AKT/mTOR信号通路
J Oncol. 2022 Sep 12;2022:6435431. doi: 10.1155/2022/6435431. eCollection 2022.
3
-Elemene Promotes Apoptosis Induced by Hyperthermia via Inhibiting HSP70.榄香烯通过抑制热休克蛋白 70 促进高温诱导的细胞凋亡。
Dis Markers. 2022 Jul 19;2022:7313026. doi: 10.1155/2022/7313026. eCollection 2022.

Retraction Note: LRPPRC regulates malignant behaviors, protects mitochondrial homeostasis, mitochondrial function in osteosarcoma and derived cancer stem-like cells.

作者信息

Zhao Ziyi, Sun Yingwei, Tang Jing, Yang Yuting, Xu Xiaochao

机构信息

TCM Regulating Metabolic Diseases Key Laboratory of Sichuan Province, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, 610041, People's Republic of China.

Department of Pharmacy, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, 610041, People's Republic of China.

出版信息

BMC Cancer. 2025 Jan 14;25(1):79. doi: 10.1186/s12885-025-13492-7.

DOI:10.1186/s12885-025-13492-7
PMID:39810116
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11731395/
Abstract
摘要