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[实验动物血管和神经的显微外科手术及其在整形手术中的重要性]

[Experimental microsurgery of blood vessels and nerves in laboratory animals and their importance for plastic surgery].

作者信息

Karl P, Tilgner-Peter A

出版信息

Z Exp Chir. 1979;12(6):368-78.

PMID:398102
Abstract

The authors give a survey of the suitability and use of different laboratory animals in the transplantation with microvascular and microneurovascular anastomoses of island flaps, muscles and composite grafts as musculo-cutaneous and osteo-musculo-cutaneous ones. This report includes the rat, rabbit, dog and pig. Preferable for learning and training suture techniques of microvessels and nerves are rats. Quite suitable in experimental research is the "epigastric" flap of rats and rabbits. Transplantations of muscles and composite grafts as musculo-cutaneous and osteo-musculo-cutaneous ones, with microvascular and microneurovascular anastomoses have been performed mostly in dogs. In order to find out suitable donor sites for microvascular and microneurovascular free flap transplantation the pig is used, showing a pattern of skin vessels most similar to that of man. But only few laboratories might be able to carry out experiments in pigs.

摘要

作者综述了不同实验动物在岛状皮瓣、肌肉以及肌皮和骨肌皮复合移植的微血管和微神经血管吻合移植中的适用性及应用情况。本报告涵盖大鼠、兔子、狗和猪。大鼠适合用于学习和训练微血管及神经的缝合技术。大鼠和兔子的“腹壁”皮瓣非常适合用于实验研究。肌肉以及肌皮和骨肌皮复合移植的微血管和微神经血管吻合移植大多在狗身上进行。为了找到适合微血管和微神经血管游离皮瓣移植的供区,人们使用猪,因为猪的皮肤血管模式与人的最为相似。但只有少数实验室能够开展猪实验。

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1
[Experimental microsurgery of blood vessels and nerves in laboratory animals and their importance for plastic surgery].[实验动物血管和神经的显微外科手术及其在整形手术中的重要性]
Z Exp Chir. 1979;12(6):368-78.
2
Practical microsurgery.实用显微外科学
Clin Plast Surg. 1976 Jan;3(1):39-47.
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Effect of diameter of microvascular interposition vein grafts on vessel patency and free flap survival in the rat model.大鼠模型中微血管插入静脉移植物直径对血管通畅性和游离皮瓣存活的影响。
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[Laboratory model of a microvascular free flap in the rat: the epigastric flap].[大鼠微血管游离皮瓣的实验模型:腹壁皮瓣]
Minerva Chir. 2002 Aug;57(4):537-41.
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The epigastric fat transfer: an alternative free flap model in the rat.上腹部脂肪转移:大鼠中的一种替代游离皮瓣模型。
Ann Plast Surg. 1992 Oct;29(4):293-6.
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Kinking of pedicle vessels and its effect on blood flow and patency in free flaps: an experimental study in rats.蒂部血管扭结及其对游离皮瓣血流和通畅性的影响:大鼠实验研究
J Craniomaxillofac Surg. 2004 Apr;32(2):94-7. doi: 10.1016/j.jcms.2003.12.001.
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Experimental prevention of free flap thrombosis. II: Normovolemic hemodilution for thrombosis prevention.游离皮瓣血栓形成的实验性预防。II:预防血栓形成的正常血容量血液稀释法。
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