Karl P, Tilgner-Peter A
Z Exp Chir. 1979;12(6):368-78.
The authors give a survey of the suitability and use of different laboratory animals in the transplantation with microvascular and microneurovascular anastomoses of island flaps, muscles and composite grafts as musculo-cutaneous and osteo-musculo-cutaneous ones. This report includes the rat, rabbit, dog and pig. Preferable for learning and training suture techniques of microvessels and nerves are rats. Quite suitable in experimental research is the "epigastric" flap of rats and rabbits. Transplantations of muscles and composite grafts as musculo-cutaneous and osteo-musculo-cutaneous ones, with microvascular and microneurovascular anastomoses have been performed mostly in dogs. In order to find out suitable donor sites for microvascular and microneurovascular free flap transplantation the pig is used, showing a pattern of skin vessels most similar to that of man. But only few laboratories might be able to carry out experiments in pigs.
作者综述了不同实验动物在岛状皮瓣、肌肉以及肌皮和骨肌皮复合移植的微血管和微神经血管吻合移植中的适用性及应用情况。本报告涵盖大鼠、兔子、狗和猪。大鼠适合用于学习和训练微血管及神经的缝合技术。大鼠和兔子的“腹壁”皮瓣非常适合用于实验研究。肌肉以及肌皮和骨肌皮复合移植的微血管和微神经血管吻合移植大多在狗身上进行。为了找到适合微血管和微神经血管游离皮瓣移植的供区,人们使用猪,因为猪的皮肤血管模式与人的最为相似。但只有少数实验室能够开展猪实验。