Fathallah Ibrahim, Qatza Ayham, Al-Talep Ahmed, Alajrd Abd Alrhman, Alfattal Mohammad, Alhamoud Ahmad
Faculty of Medicine, Homs University, Homs, Syria.
Faculty of Medicine, Hama University, Hama, Syria.
Int J Surg Case Rep. 2025 Feb;127:110890. doi: 10.1016/j.ijscr.2025.110890. Epub 2025 Jan 13.
Giant cell tumor (GCT) is a rare benign bone tumor that usually affects skeletally adult people. While it usually appears in the epiphyseal parts of long bones, it is very rare in the spine, particularly the thoracic spine, especially in pediatric patients.
An 11-year-old female presented with progressive lower extremity weakness, accompanied by localized back pain and urinary urgency, diagnosed with GCT in the thoracic spine. Magnetic resonance imaging (MRI) revealed a large, highly vascularized tumor involving the D6 and D7 vertebrae, with significant spinal cord compression. The patient underwent an urgent surgical resection of the tumor. Spinal stabilization was performed using a pedicle screw and rod construct. Postoperatively, the patient demonstrated significant improvement in muscle strength and functional recovery.
This case highlights the rarity of thoracic spine GCTs and emphasizes the critical role of MRI in diagnosis. It underscores the necessity of prompt surgical resection and spinal stabilization for patients with spinal GCT to ensure effective management and prevent neurological complications.
This report emphasizes the rarity of thoracic spine GCTs in pediatric patients, advocating for heightened clinical awareness, MRI use for early detection, and standardized management protocols to improve outcomes. Further research and education among clinicians are essential.
骨巨细胞瘤(GCT)是一种罕见的良性骨肿瘤,通常影响骨骼发育成熟的人群。虽然它通常出现在长骨的骨骺部位,但在脊柱中非常罕见,尤其是胸椎,在儿科患者中尤为罕见。
一名11岁女性出现进行性下肢无力,伴有局部背痛和尿急,被诊断为胸椎骨巨细胞瘤。磁共振成像(MRI)显示一个巨大的、血管丰富的肿瘤累及第6和第7胸椎椎体,伴有明显的脊髓受压。患者接受了紧急肿瘤手术切除。使用椎弓根螺钉和棒结构进行了脊柱稳定手术。术后,患者的肌肉力量和功能恢复有显著改善。
该病例突出了胸椎骨巨细胞瘤的罕见性,并强调了MRI在诊断中的关键作用。它强调了对于脊柱骨巨细胞瘤患者及时进行手术切除和脊柱稳定的必要性,以确保有效治疗并预防神经并发症。
本报告强调了儿科患者胸椎骨巨细胞瘤的罕见性,主张提高临床意识,使用MRI进行早期检测,并制定标准化管理方案以改善治疗效果。临床医生之间进一步的研究和教育至关重要。