Cohen J, Joyce L, Brassart G, Ruiz J C
Ann Biol Clin (Paris). 1979;37(5):291-3.
The detection of anti-HBs antibody has been carried out using a new technique where a system for the detection of HBs antigen in the solid phase is adopted to demonstrate the presence of anti HBs antibody by inhibition of the immunoenzymatic reaction. The sensitivity of the method has been compared: with that of passive haemagglutination and with that of radioimmunoassay in liquid phase, for human serum obtained from 10 chronic antibody carriers and also serum from 1 rabbit, with that of solid phase radioimmunoassay for 91 positives serums. The method appears: in the range of sensitivity of passive haemagglutination and radioimmunoassay in the liquid phase, less sensitive than that of solid phase radioimmunoassay, far superior to that of electrosyneresis.
采用一种新技术进行抗-HBs抗体检测，该技术采用固相检测HBs抗原的系统，通过抑制免疫酶反应来证明抗HBs抗体的存在。已将该方法的灵敏度与被动血凝法以及液相放射免疫分析法的灵敏度进行了比较，检测对象为10名慢性抗体携带者的人血清以及1只兔子的血清，还与91份阳性血清的固相放射免疫分析法的灵敏度进行了比较。该方法表现出：在被动血凝法和液相放射免疫分析法的灵敏度范围内，比固相放射免疫分析法的灵敏度低，但远优于电渗析法。
