Le Noc P, Croize J
Ann Biol Clin (Paris). 1979;37(5):295-301.
A micromethod utilizing paper discs impregnated with different substrates (Minitek-system) permits differentiation of Haemophilus and their biotypes. Differentiation of biotypes presents an assured advantage: it is the only technic for an exact study of non typable H. influenzae strains and NAD-dependent Haemophilus strains. It is also a complement for study of capsulated H. influenzae. In an epidemiological aspect, this differentiation shows a evident predominance of biotypes I and II for H. influenzae and H. para-influenzae. Except that biotype I includes the larger number of serotypable strains, different serotypes are distributed in the five biotypes of H. influenzae. Likewise none relation has been found between biotypes and antibiotypes.
一种利用浸渍不同底物的纸片的微量方法（Minitek 系统）可对嗜血杆菌及其生物型进行鉴别。生物型的鉴别具有确定的优势：它是精确研究不可分型流感嗜血杆菌菌株和 NAD 依赖性嗜血杆菌菌株的唯一技术。它也是研究有荚膜流感嗜血杆菌的一种补充方法。从流行病学角度来看，这种鉴别表明生物型 I 和 II 在流感嗜血杆菌和副流感嗜血杆菌中明显占优势。除了生物型 I 包含较多可分型菌株外，不同血清型分布在流感嗜血杆菌的五种生物型中。同样，未发现生物型与抗菌型之间存在关联。
