Miyazaki I, Takashima S, Takigawa Y, Kosaka T, Ueno K
Gan No Rinsho. 1985 Jan;31(1):52-6.
In order to establish method of screening for colorectal cancer, we studied clinicopathological features in 116 cases of adenoma, precancerous lesion, and in 80 cases of early colorectal cancer. The incidence of early cancer began to rise at the age of more than 40, reaching a peak in the sixth decade. The risk for men was higher than for women. In relation to the location of these lesions, 71% of the adenoma and 91% of the early cancer were in the left colon and rectum. As symptoms on admission, overt bleeding from the rectum appeared in 35% of the adenoma and in 56% of the early cancer patients, respectively. Therefore, we emphasize that it is extremely important to examine overt and occult bleeding as the first screening for colorectal cancer.
为建立结直肠癌筛查方法,我们研究了116例腺瘤(癌前病变)及80例早期结直肠癌的临床病理特征。早期癌症发病率在40岁以上开始上升,在60岁时达到峰值。男性患病风险高于女性。就这些病变的位置而言,71%的腺瘤和91%的早期癌症位于左半结肠和直肠。作为入院时的症状,分别有35%的腺瘤患者和56%的早期癌症患者出现直肠显性出血。因此,我们强调将显性和隐性出血检查作为结直肠癌的首要筛查极为重要。