Feo Alessandro, Stradiotto Elisa, Govetto Andrea, Forte Paolo, Boscia Giacomo, Nicolò Massimo, Cattaneo Jennifer, Eandi Chiara M, Angi Martina, Ramtohul Prithvi, Romano Mario R
Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, Pieve Emanuele, Milan 20072, Italy.
Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, Pieve Emanuele, Milan 20072, Italy.
Surv Ophthalmol. 2025 May-Jun;70(3):401-411. doi: 10.1016/j.survophthal.2025.01.005. Epub 2025 Jan 14.
Bacillary layer detachment (BALAD) refers to the distinctive splitting at the level of the photoreceptor inner segment myoid and accumulation of intraretinal fluid, as seen on optical coherence tomography (OCT). BALAD is an increasingly recognized OCT biomarker of numerous heterogeneous chorioretinal diseases, including posterior uveitis, age-related macular degeneration and macular neovascularization, neoplastic and paraneoplastic retinal disorders, rhegmatogenous retinal detachment, blunt ocular trauma, and miscellaneous conditions. The recognition of BALAD is clinically relevant because, based on the specific etiology, BALAD may require simple observation, ocular or systemic medical treatment, or even surgical intervention, with subsequent different prognosis. We discuss and summarize the clinical and prognostic significance of BALAD in the different chorioretinal disorders in which it has been described.
杆菌层脱离（BALAD）是指在光感受器内节肌样层水平出现的特征性劈裂以及视网膜内液体积聚，这在光学相干断层扫描（OCT）中可见。BALAD是多种异质性脉络膜视网膜疾病越来越被认可的OCT生物标志物，这些疾病包括后葡萄膜炎、年龄相关性黄斑变性和黄斑新生血管、肿瘤性和副肿瘤性视网膜疾病、孔源性视网膜脱离、钝性眼外伤以及其他各种情况。认识BALAD具有临床相关性，因为根据具体病因，BALAD可能需要单纯观察、眼部或全身药物治疗，甚至手术干预，随后会有不同的预后。我们讨论并总结了BALAD在已被描述的不同脉络膜视网膜疾病中的临床和预后意义。
