Hammer Turid, Agerbo Modin Frederikke, Rubek Nielsen Kári, Midjord Jóngerð, Langholz Ebbe, Andersen Vibeke, Dahlerup Jens Frederik, Kjeldsen Jens, Pedersen Natalia, Munkholm Pia, Burisch Johan
Department of Research, the National Hospital of the Faroe Islands, Tórshavn, Faroe Islands.
Omicron ApS, Søborg, Denmark.
Scand J Gastroenterol. 2025 Mar;60(3):225-234. doi: 10.1080/00365521.2025.2453429. Epub 2025 Jan 17.
Patients with inflammatory bowel disease (IBD) have lower health-related quality of life (HRQoL) than the general population. The highest incidence and prevalence rates of IBD in the world are found in the Faroe Islands, however, the HRQoL of Faroese patients is unknown. This study aimed to determine their HRQoL at diagnosis and two years of follow-up in comparison with Danish patients.
All patients (15 years or older) were invited to answer the Short Form 12 questionnaire (SF-12) and Short Inflammatory Bowel Disease Questionnaire (SIBDQ) at diagnosis and follow-up. Faroese patients were included from 2010 to 2022, and Danish patients in 2010.
160 Faroese patients and 160 Danish patients completed questionnaires twice. For Faroese patients with IBD, the physical and mental component summary scores (SF-12) significantly improved from 46.6 and 44.0 to 49.4 and 47.7, respectively. Total SIBDQ scores also improved from 46.6 to 53.9. However, Faroese patients had significantly lower scores at diagnosis of social functioning, mental health, and mental component summary (SF-12) as well as lower emotional scores (SIBDQ) compared with Danish patients.
Faroese patients with IBD improved their HRQoL from diagnosis to follow-up, although greater improvements were observed for Danish patients. Increased awareness of the HRQoL of this patient group is warranted as Faroese patients had lower mental and emotional scores than Danish patients at diagnosis.
炎症性肠病（IBD）患者的健康相关生活质量（HRQoL）低于普通人群。世界上IBD发病率和患病率最高的地区是法罗群岛，然而，法罗群岛患者的HRQoL尚不清楚。本研究旨在确定他们在诊断时和随访两年后的HRQoL，并与丹麦患者进行比较。
所有15岁及以上的患者在诊断和随访时均被邀请回答简明健康调查量表（SF-12）和炎症性肠病简短问卷（SIBDQ）。纳入了2010年至2022年的法罗群岛患者以及2010年的丹麦患者。
160名法罗群岛患者和160名丹麦患者完成了两次问卷调查。对于患有IBD的法罗群岛患者，其身体和心理成分汇总得分（SF-12）分别从46.6和44.0显著提高到49.4和47.7。SIBDQ总分也从46.6提高到53.9。然而，与丹麦患者相比，法罗群岛患者在社会功能、心理健康和心理成分汇总（SF-12）诊断时得分显著更低，情感得分（SIBDQ）也更低。
患有IBD的法罗群岛患者从诊断到随访期间HRQoL有所改善，尽管丹麦患者的改善更为明显。鉴于法罗群岛患者在诊断时的心理和情感得分低于丹麦患者，有必要提高对该患者群体HRQoL的认识。
