Hayes L J, Valvano J W
J Biomech Eng. 1985 Feb;107(1):77-80. doi: 10.1115/1.3138524.
The purpose of this work is to validate, using numerical, finite element methods, the thermal assumptions made in the analytical analysis of a coupled thermistor probe-tissue model upon which a thermal conductivity measurement scheme has been based. Analytic, closed form temperature profiles generated by the self-heated thermistors can be found if three simplifying assumptions are made: the thermistor is spherical; heat is generated in all regions of the bead; and heat is generated uniformly in the bead. This analytic solution is used to derive a linear relationship between tissue thermal conductivity and the ratio of thermistor temperature rise over electrical power required to maintain that temperature rise. This derived, linear relationship is used to determine thermal conductivity from the observed experimental data. However, in reality, the thermistor bead is a prolate spheroid surrounded by a passive shell, and the heating pattern in the bead is highly nonuniform. In the physical system, the exact relationship between the tissue thermal conductivity and parameters measured by the thermistor is not known. The finite element method was used to calculate the steady-state temperature profiles generated by thermistor beads with realistic geometry and heating patterns. The results of the finite element analysis show that the empirical, linear relationship remains valid when all three simplified assumptions are significantly relaxed.
这项工作的目的是使用数值有限元方法验证在热导率测量方案所基于的耦合热敏电阻探头 - 组织模型的分析分析中所做的热假设。如果做出三个简化假设,就可以找到由自热热敏电阻产生的解析封闭形式温度分布:热敏电阻是球形的;在珠体的所有区域产生热量;并且在珠体中均匀产生热量。该解析解用于推导组织热导率与热敏电阻温度升高与维持该温度升高所需电功率之比之间的线性关系。这个推导出来的线性关系用于从观察到的实验数据中确定热导率。然而,实际上,热敏电阻珠是一个被无源外壳包围的长椭球体,并且珠体中的加热模式是高度不均匀的。在物理系统中,组织热导率与热敏电阻测量参数之间的确切关系尚不清楚。有限元方法用于计算具有实际几何形状和加热模式的热敏电阻珠产生的稳态温度分布。有限元分析结果表明,当所有三个简化假设都被显著放宽时,经验线性关系仍然有效。