Fiek M, Gindele F, von Bary C, Muessig D, Lucic A, Hoffmann E, Reithmann C, Steinbeck G
Medical Hospital I, Klinikum Pasing, Steinerweg 5, 81241, Munich, Germany,
J Interv Card Electrophysiol. 2013 Oct;38(1):53-9. doi: 10.1007/s10840-013-9815-5. Epub 2013 Jul 14.
For the treatment of increasingly complex cardiac arrhythmias, new catheter designs as well as alternative energy sources are constantly being developed. However, there is presently no in vitro method available for assessment of the temperature changes induced at various myocardial levels during energy delivery. Therefore, our study was aimed at developing an in vitro model to record and display the temperature kinetics during ablation in the entire muscle cross section.
A sapphire glass pane was inserted into one wall of the in vitro experimental set-up. Due to its thermodynamic properties, the temperature distribution in an adjacent cross section of the cardiac muscle can be measured exactly ( 1 °C) through this pane by means of a thermography camera. Computer-supported image processing enables the colour-coded and two-dimensional display of the temperature kinetics during the energy application at any location of the myocardial cross section (± 0.5 mm). This new measuring methodology was validated by direct temperature measurements utilizing several intramyocardial thermo elements.
This new method allows a temporal and spatial analysis of the temperature phenomena during ablation without the interference and spatial limitation of intramyocardial temperature probes. New ablation technologies can thus be evaluated, independent of the catheter configuration or source of energy used.
为了治疗日益复杂的心律失常,新型导管设计以及替代能源不断涌现。然而,目前尚无体外方法可用于评估能量传递过程中不同心肌层面所诱导的温度变化。因此,我们的研究旨在建立一种体外模型,以记录并显示整个肌肉横截面消融过程中的温度动力学。
将一块蓝宝石玻璃板插入体外实验装置的一侧壁。凭借其热力学特性,可通过该玻璃板借助热成像相机精确测量(精确至1℃)相邻心肌横截面的温度分布。计算机辅助图像处理能够以颜色编码的二维方式显示心肌横截面任何位置(±0.5毫米)在能量施加过程中的温度动力学。利用多个心内温度元件进行直接温度测量,验证了这种新的测量方法。
这种新方法能够在不受心内温度探头干扰和空间限制的情况下,对消融过程中的温度现象进行时空分析。因此,无需考虑导管配置或所使用的能源,即可评估新型消融技术。