Belteki Z, Ward E K, Begum-Ali J, van den Boomen C, Bölte S, Buitelaar J, Charman T, Demurie E, Falck-Ytter T, Hunnius S, Johnson M H, Jones E J H, Oosterling I, Pasco G, Pijl M K J, Radkowska A, Rudling M, Tomalski P, Warreyn P, Junge C, Haman E
Faculty of Experimental Psychology, Helmholtz Institute, Utrecht University, Utrecht, Netherlands.
Department of Psychological Sciences, Birkbeck, University of London, London, England.
J Autism Dev Disord. 2025 Jan 17. doi: 10.1007/s10803-024-06652-4.
Infants at elevated likelihood for or later diagnosed with autism typically have smaller vocabularies than their peers, as shown by the Mullen Scales of Early Learning (MSEL) and the MacArthur-Bates Communicative Developmental Inventory (CDI). However, the extent to which MSEL and CDI scores align remains unclear, especially across clinical and non-clinical populations. This study examined whether the concurrent validity of the MSEL and CDI differs based on autism likelihood and diagnosis. Data from 720 14-month-old infants were analysed, grouped by likelihood (elevated vs. typical) and diagnosis at 36 months (diagnosed vs. not diagnosed). Vocabulary scores were compared across both likelihood and diagnostic groups. Moderate correlations were observed between the MSEL and CDI in most groups (r range = [.34-.58]). One exception was that the expressive scores of elevated likelihood infants on the MSEL and CDI were more closely associated than the expressive scores of typical likelihood infants. Diagnosed infants had lower vocabulary scores than non-diagnosed peers on both the MSEL and CDI. The elevated likelihood group showed lower scores on the MSEL but not the CDI compared to typical likelihood infants. The moderate correlations suggest that the MSEL and CDI assess different aspects of language in infancy. These associations were weaker than previously reported in autistic children. Differences in vocabulary scores across likelihood and diagnostic groups highlight the need for further research to understand the association between these measures.
如《早期学习穆伦量表》（MSEL）和《麦克阿瑟-贝茨交流发展量表》（CDI）所示，自闭症患病可能性较高或后来被诊断为自闭症的婴儿，其词汇量通常比同龄人小。然而，MSEL和CDI分数的一致程度仍不清楚，尤其是在临床和非临床人群中。本研究调查了MSEL和CDI的同时效度是否因自闭症患病可能性和诊断情况而异。对720名14个月大婴儿的数据进行了分析，根据36个月时的患病可能性（高风险与正常）和诊断结果（确诊与未确诊）进行分组。比较了不同患病可能性和诊断组之间的词汇分数。在大多数组中，MSEL和CDI之间观察到中等程度的相关性（r范围 = [.34-.58]）。一个例外是，高风险婴儿在MSEL和CDI上的表达分数比正常风险婴儿的表达分数更密切相关。在MSEL和CDI上，确诊婴儿的词汇分数均低于未确诊的同龄人。与正常风险婴儿相比，高风险组在MSEL上的分数较低，但在CDI上没有差异。中等程度的相关性表明，MSEL和CDI评估了婴儿期语言的不同方面。这些关联比先前在自闭症儿童中报告的要弱。不同患病可能性和诊断组之间词汇分数的差异凸显了进一步研究以了解这些测量方法之间关联的必要性。
