文献检索文档翻译深度研究
Suppr Zotero 插件Zotero 插件
邀请有礼套餐&价格历史记录

新学期,新优惠

限时优惠:9月1日-9月22日

30天高级会员仅需29元

1天体验卡首发特惠仅需5.99元

了解详情
不再提醒
插件&应用
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
高级版
套餐订阅购买积分包
AI 工具
文献检索文档翻译深度研究
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2025

利多卡因-地塞米松与利多卡因-曲安奈德预防脊髓硬膜外腔阻滞术后背痛的比较:一项随机研究。

Comparison of Lignocaine-Dexamethasone vs. Lignocaine-Triamcinolone for Preventing Post Spinal-Epidural Backache: A Randomized Study.

作者信息

Soni Ankit, Singh Brijesh P, Srivastava Vinod K, Prakash Ravi, Gautam Shefali, Singh Gyan Prakash

机构信息

Anaesthesiology, King George's Medical University, Lucknow, IND.

出版信息

Cureus. 2024 Dec 17;16(12):e75877. doi: 10.7759/cureus.75877. eCollection 2024 Dec.


DOI:10.7759/cureus.75877
PMID:39822438
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11738074/
Abstract

BACKGROUND: The primary objective of this study was to compare the efficacy of lignocaine-dexamethasone and lignocaine-triamcinolone infiltration, along the spinal-epidural needle insertion pathway, to prevent backache after lower abdominal surgeries. METHODS: This prospective, double-blind randomized controlled study included a total of 150 patients, scheduled for elective lower abdominal surgery under combined spinal-epidural (CSE) anaesthesia. The patients were randomised into three groups Group L (Lignocaine, n=50), Group DL (Dexamethasone, Lignocaine, n=50), and Group TL (Triamcinolone, Lignocaine, n=50). RESULTS: The Visual Analogue Score (VAS) was used to assess the postoperative pain. The anthropometric and demographic findings were comparable among the three groups. The mean VAS score at the time points of needle placement and at postoperative time periods of 24 hours, 48 hours, 72 hours, one month, two months and three months were significantly lower (p<0.001) in groups DL and TL compared to group L. CONCLUSION: This study demonstrated that the addition of a steroid like triamcinolone or dexamethasone with lignocaine for local infiltration along the spinal-epidural tract significantly lowers the severity of post-needle puncture backache in comparison to lignocaine alone in lower abdominal surgeries.

摘要

背景:本研究的主要目的是比较利多卡因-地塞米松和利多卡因-曲安奈德沿腰麻-硬膜外穿刺针进针路径进行浸润,预防下腹部手术后背痛的效果。 方法:这项前瞻性、双盲随机对照研究共纳入150例计划在腰麻-硬膜外联合麻醉下行择期下腹部手术的患者。患者被随机分为三组:L组(利多卡因,n = 50)、DL组(地塞米松、利多卡因,n = 50)和TL组(曲安奈德、利多卡因,n = 50)。 结果:采用视觉模拟评分法(VAS)评估术后疼痛。三组患者的人体测量学和人口统计学结果具有可比性。与L组相比,DL组和TL组在穿刺时以及术后24小时、48小时、72小时、1个月、2个月和3个月时的平均VAS评分显著降低(p < 0.001)。 结论:本研究表明,在下腹部手术中,与单独使用利多卡因相比,在利多卡因中添加曲安奈德或地塞米松等类固醇进行腰麻-硬膜外穿刺路径局部浸润,可显著降低穿刺后背痛的严重程度。

相似文献

[1]
Comparison of Lignocaine-Dexamethasone vs. Lignocaine-Triamcinolone for Preventing Post Spinal-Epidural Backache: A Randomized Study.

Cureus. 2024-12-17

[2]
Dexamethasone added to local lidocaine for infiltration along the spinal-epidural needle pathway decreases incidence and severity of backache after gynecological surgery.

Med Sci Monit. 2015-3-18

[3]
Epidural dexamethasone reduces the incidence of backache after lumbar epidural anesthesia.

Anesth Analg. 1997-2

[4]
Comparison of the effects of intravenous lignocaine and ketamine on postoperative pain after lower abdominal surgeries under general anaesthesia.

Indian J Anaesth. 2023-2

[5]
A comparative evaluation of the effect of addition of 8 mg dexamethasone to 2% lignocaine with adrenaline in mandibular third molar surgery: a split mouth randomised double blind study.

Front Oral Health. 2024-2-9

[6]
Role of addition of Dexamethasone and Ketorolac to lignocaine intravenous regional anesthesia (Bier's Block) to improve tourniquet tolerance and post-operative analgesia in hand and forearm surgery.

J Pak Med Assoc. 2015-11

[7]
Intravenous Lignocaine-Fentanyl Versus Epidural Ropivacaine-Fentanyl for Postoperative Analgesia After Major Abdominal Oncosurgery: A Pilot Prospective Randomised Study.

Turk J Anaesthesiol Reanim. 2021-4

[8]
Comparative effectiveness of lumbar transforaminal epidural steroid injections with particulate versus nonparticulate corticosteroids for lumbar radicular pain due to intervertebral disc herniation: a prospective, randomized, double-blind trial.

Pain Med. 2014-1-2

[9]
Do we need cephalic spread of spinal anaesthesia for caesarean section? A different approach to CSE-EVE for reducing hypotension.

Z Geburtshilfe Neonatol. 2013-8

[10]
A comparative study of two different doses of epidural neostigmine coadministered with lignocaine for post operative analgesia and sedation.

J Anaesthesiol Clin Pharmacol. 2010-10

引用本文的文献

[1]
Multifunctional Magnetic Nanoparticles for Targeted Drug Delivery Against Cancer: A Review of Mechanisms, Applications, Consequences, Limitations, and Tailoring Strategies.

Ann Biomed Eng. 2025-6

本文引用的文献

[1]
Comparison of postoperative back pain between paramedian and midline approach for thoracic epidural anesthesia.

Anesth Pain Med (Seoul). 2022-7

[2]
The Incidence of and Risk Factors for Localized Pain at the Epidural Insertion Site After Epidural Anesthesia: A Prospective Survey of More Than 5000 Cases in Nonobstetric Surgery.

Risk Manag Healthc Policy. 2021-5-25

[3]
Short-Term Efficacy of Epidural Injection of Triamcinolone Through Translaminar Approach for the Treatment of Lumbar Canal Stenosis.

Anesth Pain Med. 2020-2-29

[4]
Pain reduction after lumbar epidural injections using particulate versus non-particulate steroids: intensity of the baseline pain matters.

Eur Radiol. 2019-3-18

[5]
Efficacy of epidural local anesthetic and dexamethasone in providing postoperative analgesia: A meta-analysis.

Saudi J Anaesth. 2016

[6]
A Randomized Clinical Trial of Three Different Steroid Agents for Treatment of Low Backache through the Caudal Route.

Med J Armed Forces India. 2011-1

[7]
Serum Triamcinolone Levels Following Interlaminar Epidural Injection.

Reg Anesth Pain Med. 2016

[8]
Dexamethasone added to local lidocaine for infiltration along the spinal-epidural needle pathway decreases incidence and severity of backache after gynecological surgery.

Med Sci Monit. 2015-3-18

[9]
Perineural dexamethasone added to local anesthesia for brachial plexus block improves pain but delays block onset and motor blockade recovery.

Pain Physician. 2015

[10]
Blocking the mineralocorticoid receptor improves effectiveness of steroid treatment for low back pain in rats.

Anesthesiology. 2014-9

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

推荐工具

医学文档翻译智能文献检索