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硬膜外麻醉后硬膜外穿刺部位局部疼痛的发生率及危险因素:对5000多例非产科手术病例的前瞻性调查

The Incidence of and Risk Factors for Localized Pain at the Epidural Insertion Site After Epidural Anesthesia: A Prospective Survey of More Than 5000 Cases in Nonobstetric Surgery.

作者信息

Kang Xianhui, Zhu Yeke, Lin Kun, Xie Liwei, Wen Heng, Geng Wujun, Zhu Shengmei

机构信息

Department of Anesthesiology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, People's Republic of China.

Department of Anesthesiology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, People's Republic of China.

出版信息

Risk Manag Healthc Policy. 2021 May 25;14:2171-2180. doi: 10.2147/RMHP.S290763. eCollection 2021.

Abstract

BACKGROUND

This prospective research aimed to determine the incidence of and risk factors for localized pain at the epidural insertion site following nonobstetric surgery performed with epidural anesthesia.

METHODS

A total of 5083 surgical inpatients at the teaching hospital undergoing epidural anesthesia were included in the study. The characteristics of the patients, preoperative basic diseases, details of the epidural techniques, surgical procedures and complications were recorded pre-anesthesia until the complications resolved. Multivariate logistic regression analysis was performed to identify predictors of localized pain at the epidural insertion site.

RESULTS

In our analysis, target complications were reported in 532 (10.5%) patients; localized pain at the epidural insertion site occurred in 460 (9.05%) patients, while other major complications occurred in 72 (1.45%) patients. A total of 334 patients had mild pain, and 126 patients had moderate pain. The incidence of localized pain at the epidural insertion site was highest among all complications, and the identified risk factors in the multivariate analysis were as follows: lumbar insertion (odds ratio, 1.77; 95% CI 1.33-2.35), age less than 50 years old (odds ratio, 1.56; 95% CI 1.29-1.89), multiple block attempts (odds ratio, 3.39; 95% CI 2.68-4.31), and postoperative patient-controlled epidural analgesia (odds ratio, 0.46; 95% CI 0.33-0.63).

CONCLUSION

Localized pain at the epidural insertion site is the most common complaint after epidural anesthesia and requires adequate clinical attention. Improving the proficiency of anesthesiologists to avoid repeated punctures is the best way to reduce injuries.

摘要

背景

本前瞻性研究旨在确定硬膜外麻醉下非产科手术后硬膜外穿刺部位局部疼痛的发生率及危险因素。

方法

本研究纳入了教学医院接受硬膜外麻醉的5083例外科住院患者。记录患者的特征、术前基础疾病、硬膜外技术细节、手术过程及并发症,记录时间从麻醉前至并发症解决。进行多因素逻辑回归分析以确定硬膜外穿刺部位局部疼痛的预测因素。

结果

在我们的分析中,532例(10.5%)患者报告了目标并发症;460例(9.05%)患者发生了硬膜外穿刺部位局部疼痛,而72例(1.45%)患者发生了其他主要并发症。共有334例患者有轻度疼痛,126例患者有中度疼痛。硬膜外穿刺部位局部疼痛的发生率在所有并发症中最高,多因素分析确定的危险因素如下:腰椎穿刺(比值比,1.77;95%可信区间1.33 - 2.35)、年龄小于50岁(比值比,1.56;95%可信区间1.29 - 1.89)、多次阻滞尝试(比值比,3.39;95%可信区间2.68 - 4.31)以及术后患者自控硬膜外镇痛(比值比,0.46;95%可信区间0.33 - 0.63)。

结论

硬膜外穿刺部位局部疼痛是硬膜外麻醉后最常见的主诉,需要临床给予充分关注。提高麻醉医生的操作熟练度以避免反复穿刺是减少损伤的最佳方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d20/8164713/ed02fd37ba35/RMHP-14-2171-g0001.jpg

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