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评估冲击波碎石术与输尿管镜碎石术治疗肾结石的有效性:一项前瞻性队列研究。

Evaluating the Effectiveness of Shockwave Lithotripsy vs Ureteroscopic Lithotripsy for Treatment of Renal Stones: A Prospective Cohort Study.

作者信息

Ahmed Butt Naeem, Wajiha Batool Syeda, Ali Akbar Aiza, Amir Muhammad, Qayyum Yasir, Akbar Amna, Khan Marriam, Ali Hasnain

机构信息

Department of Urology, Abbas Institute of Medical Sciences, Islamabad, PAK.

Medicine, Azad Jammu Kashmir Medical College, Muzaffarabad, PAK.

出版信息

Cureus. 2024 Dec 17;16(12):e75876. doi: 10.7759/cureus.75876. eCollection 2024 Dec.

Abstract

BACKGROUND

Renal stones are a prevalent condition requiring effective treatment strategies. This study evaluates the comparative effectiveness of shockwave lithotripsy (SWL) and ureteroscopic lithotripsy (URSL) in treating renal stones in a Pakistani cohort, focusing on stone clearance, recurrence, and complications.

METHODS

This prospective cohort study involved 250 patients aged 18-55 diagnosed with renal stones. Participants were divided into two groups based on treatment selection (SWL or URSL) and followed for 12 months. Primary outcomes included stone clearance rates, while secondary outcomes encompassed recurrence and complications. Statistical analyses, including chi-square tests and Mann-Whitney U tests, assessed demographic and clinical characteristics, with significance set at p < 0.05.

RESULTS

The mean age of participants was 35.05 years, with an equal distribution between SWL and URSL groups. Both treatments demonstrated similar stone clearance rates, with no significant difference in success (p > 0.05). Complications were noted in 64.4% of cases, with bleeding (34.0%) and infection (30.4%) as the most frequent issues. Recurrence rates were comparable (p = 0.800), affecting 49.2% of patients. Re-treatment was required in 51.2% of cases, equally distributed between the groups.

CONCLUSION

SWL and URSL exhibit comparable effectiveness in treating renal stones, with similar success and recurrence rates. While complications were common, they were manageable. Both approaches are effective options for renal stone management, emphasizing the need for individualized treatment decisions based on patient and stone characteristics.

摘要

背景

肾结石是一种普遍存在的疾病,需要有效的治疗策略。本研究评估了冲击波碎石术(SWL)和输尿管镜碎石术(URSL)在巴基斯坦队列中治疗肾结石的相对有效性,重点关注结石清除率、复发率和并发症。

方法

这项前瞻性队列研究纳入了250名年龄在18至55岁之间被诊断为肾结石的患者。参与者根据治疗选择(SWL或URSL)分为两组,并随访12个月。主要结局包括结石清除率,次要结局包括复发率和并发症。统计分析,包括卡方检验和曼-惠特尼U检验,评估了人口统计学和临床特征,显著性设定为p < 0.05。

结果

参与者的平均年龄为35.05岁,SWL组和URSL组分布均衡。两种治疗方法的结石清除率相似,成功率无显著差异(p > 0.05)。64.4%的病例出现并发症,出血(34.0%)和感染(30.4%)是最常见的问题。复发率相当(p = 0.800),影响了49.2%的患者。51.2%的病例需要再次治疗,两组分布均匀。

结论

SWL和URSL在治疗肾结石方面表现出相当的有效性,成功率和复发率相似。虽然并发症很常见,但可以控制。两种方法都是肾结石治疗的有效选择,强调需要根据患者和结石特征做出个体化的治疗决策。

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