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Fully automatic deep learning-based lung parenchyma segmentation and boundary correction in thoracic CT scans.基于深度学习的全自动化肺部组织分割和胸 CT 扫描边界修正。
Int J Comput Assist Radiol Surg. 2024 Feb;19(2):261-272. doi: 10.1007/s11548-023-03010-0. Epub 2023 Aug 18.
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Circulating proteome for pulmonary nodule malignancy.循环蛋白质组学在肺结节良恶性诊断中的应用
J Natl Cancer Inst. 2023 Sep 7;115(9):1060-1070. doi: 10.1093/jnci/djad122.
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Preoperative diagnosis of solitary pulmonary nodules with a novel hematological index model based on circulating tumor cells.基于循环肿瘤细胞的新型血液学指标模型对孤立性肺结节的术前诊断
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基于影像后处理系统的CT诊断技术在肺癌早期诊断与治疗中的价值。

Value of CT diagnostic techniques based on imaging post-processing systems in the early diagnosis and treatment of lung cancer.

作者信息

Li Wanling, Zheng Xuelan, Huang Jishui

机构信息

Computed Magnetic Resonance Imaging Tomography, The Second Affiliated Hospital of Fujian Medical University Quanzhou 362000, Fujian, China.

Intensive Care Unit, The Second Affiliated Hospital of Fujian Medical University Quanzhou 362000, Fujian, China.

出版信息

Am J Transl Res. 2024 Dec 15;16(12):7396-7404. doi: 10.62347/VJSR2965. eCollection 2024.

DOI:10.62347/VJSR2965
PMID:39822500
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11733320/
Abstract

OBJECTIVE

To evaluate the application value of CT diagnostic technology based on the Shukun Imaging Post-Processing System for early screening and diagnosis of lung cancer.

METHODS

A total of 35 patients diagnosed with lung cancer postoperatively and 53 patients with benign nodules were included in this retrospective study, all of whom were treated in the Department of Thoracic and Cardiovascular Surgery of the Second Affiliated Hospital of Fujian Medical University from January 2020 to December 2023. All patients underwent chest spiral CT examinations. Original thin-slice axial CT images were processed using Shukun software for three-dimensional reconstruction of the lesions, surrounding lung tissue, and trachea. The diagnoses and malignant risk indicators of pulmonary nodules were established based on the final imaging results.

RESULTS

Statistical analysis showed that the sensitivity of Shukun processing technology in diagnosing early-stage lung cancer was 82.86%, with a specificity of 88.46%, when compared to postoperative pathological analysis. Univariate logistic regression analysis indicated that features such as burr sign, lobulation sign, pleural traction sign, vascular convergence sign, vacuole sign, and nodule size derived from Shukun processing had significant predictive value for malignant nodules (P<0.05).

CONCLUSION

Shukun processing technology can effectively reconstruct ordinary CT tomographic images into three-dimensional representations, enhancing the visualization of spatial relationships between the tumor and adjacent anatomical structures, including trachea, pleura, bronchi, and blood vessels. It has high clinical diagnostic value for the early diagnosis of malignant pulmonary nodules.

摘要

目的

评估基于舒坤影像后处理系统的CT诊断技术在肺癌早期筛查和诊断中的应用价值。

方法

本回顾性研究纳入了35例术后确诊为肺癌的患者和53例良性结节患者,所有患者均于2020年1月至2023年12月在福建医科大学附属第二医院胸心外科接受治疗。所有患者均接受胸部螺旋CT检查。使用舒坤软件对原始薄层轴向CT图像进行处理,以对病变、周围肺组织和气管进行三维重建。根据最终影像结果确定肺结节的诊断及恶性风险指标。

结果

统计分析显示,与术后病理分析相比,舒坤处理技术诊断早期肺癌的敏感性为82.86%,特异性为88.46%。单因素逻辑回归分析表明,源自舒坤处理的毛刺征、分叶征、胸膜牵拉征、血管集束征、空泡征及结节大小等特征对恶性结节具有显著预测价值(P<0.05)。

结论

舒坤处理技术可有效将普通CT断层图像重建为三维图像,增强肿瘤与包括气管、胸膜、支气管和血管在内的相邻解剖结构之间空间关系的可视化。它对恶性肺结节的早期诊断具有较高的临床诊断价值。