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一名患有格里塞尔综合征儿童的斜颈:病例报告及文献综述

Torticollis in a child with Grisel syndrome: A case report and review of the literature.

作者信息

Budha Bishal, Paudel Sujan, Luitel Prajjwol, Joshi Bishweshwar, Upreti Arun, Ghimire Nischal

机构信息

Maharajgunj Medical Campus, Institute of Medicine, Tribhuvan University, Maharajgunj, Nepal.

Maharajgunj Medical Campus, Institute of Medicine, Tribhuvan University, Maharajgunj, Nepal.

出版信息

Int J Surg Case Rep. 2025 Feb;127:110817. doi: 10.1016/j.ijscr.2025.110817. Epub 2025 Jan 4.

DOI:10.1016/j.ijscr.2025.110817
PMID:39823970
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11786686/
Abstract

INTRODUCTION AND IMPORTANCE

Grisel syndrome (GS) is a rare but potentially lethal condition characterized by non-traumatic atlantoaxial subluxation primarily affecting pediatric population following inflammatory condition of head and neck. Early diagnosis and prompt treatment is crucial for better management of symptoms and better outcomes.

CASE PRESENTATION

7-years-old child present with torticollis, sudden onset progressive neck pain, restricted range of motion and bilateral lymphadenopathy after upper respiratory tract infection (URTI). Radiological findings revealed 1st and 2nd cervical vertebrae (C1-C2) subluxation and he was diagnosed as GS. He was managed conservatively with head halter and soft collar, resulting full recovery within 2 weeks.

CLINICAL DISCUSSION

Grisel syndrome should be considered in pediatric population presenting with neck pain and torticollis following URTI or surgery, demanding early radiological imaging and prompt treatment to prevent complications.

CONCLUSION

Early diagnosis and prompt treatment alleviates neurological complications and necessity of surgical intervention.

摘要

引言与重要性

格里斯尔综合征(GS)是一种罕见但可能致命的疾病,其特征为非创伤性寰枢椎半脱位,主要影响头颈部炎症后的儿童人群。早期诊断和及时治疗对于更好地控制症状和取得更好的治疗效果至关重要。

病例介绍

一名7岁儿童在上呼吸道感染(URTI)后出现斜颈、突发进行性颈部疼痛、活动范围受限和双侧淋巴结病。影像学检查发现第一和第二颈椎(C1-C2)半脱位,被诊断为GS。采用头部颈托和软颈圈进行保守治疗,2周内完全康复。

临床讨论

对于URTI或手术后出现颈部疼痛和斜颈的儿童,应考虑格里斯尔综合征,需要早期进行影像学检查并及时治疗以预防并发症。

结论

早期诊断和及时治疗可减轻神经并发症以及手术干预的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb58/11786686/418f40e82f6d/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb58/11786686/3eddd0c1fdb4/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb58/11786686/224ec0075a3e/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb58/11786686/066733c0b7f9/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb58/11786686/afa50fc469d9/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb58/11786686/c2eb490f079a/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb58/11786686/418f40e82f6d/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb58/11786686/3eddd0c1fdb4/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb58/11786686/224ec0075a3e/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb58/11786686/066733c0b7f9/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb58/11786686/afa50fc469d9/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb58/11786686/c2eb490f079a/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb58/11786686/418f40e82f6d/gr6.jpg

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本文引用的文献

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A Rare Case of Grisel's Syndrome in A 6-Year-Old Child.一名6岁儿童的罕见格里斯尔综合征病例。
J Orthop Case Rep. 2024 Jan;14(1):137-140. doi: 10.13107/jocr.2024.v14.i01.4176.
2
Diagnostic Approach and Treatment Options for Pediatric Cases of Grisel's Syndrome Post Otolaryngology Procedure: A Systematic Review.耳鼻喉科手术后小儿格里斯尔综合征病例的诊断方法与治疗选择:一项系统评价
Cureus. 2024 Jan 6;16(1):e51739. doi: 10.7759/cureus.51739. eCollection 2024 Jan.
3
Grisel's syndrome and Down syndrome: a case report.格里塞尔综合征与唐氏综合征:一例报告
Int J Burns Trauma. 2023 Apr 15;13(2):94-98. eCollection 2023.
4
Torticollis in an 8-year-old child due to Grisel's syndrome - A case report.一名8岁儿童因格里塞尔综合征导致的斜颈——病例报告
Surg Neurol Int. 2022 Nov 4;13:502. doi: 10.25259/SNI_805_2022. eCollection 2022.
5
Grisel's syndrome associated with mumps: A case report.与腮腺炎相关的格里斯尔综合征:一例报告。
Front Pediatr. 2022 Sep 29;10:916538. doi: 10.3389/fped.2022.916538. eCollection 2022.
6
Surgical management of Grisel syndrome in the adult patient: illustrative case.成年患者格里斯尔综合征的手术治疗:病例说明
J Neurosurg Case Lessons. 2022 Mar 7;3(10). doi: 10.3171/CASE21692.
7
Conservative approach for treatment of Grisel's syndrome after resection of lympahadenitis tuberculosis of the neck: A rare case report.颈部淋巴结结核切除术后格里斯尔综合征的保守治疗方法:1例罕见病例报告
Int J Surg Case Rep. 2021 Nov;88:106452. doi: 10.1016/j.ijscr.2021.106452. Epub 2021 Oct 1.
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Magnetic Resonance Imaging as the Primary Imaging Modality in Children Presenting with Inflammatory Nontraumatic Atlantoaxial Rotatory Subluxation.磁共振成像作为炎症性非创伤性寰枢椎旋转半脱位患儿的主要影像学检查方法
Children (Basel). 2021 Apr 23;8(5):329. doi: 10.3390/children8050329.
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Grisel's syndrome in adults: A case report.成人格里塞尔综合征:一例报告。
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Grisel's Syndrome in Children: Two Case Reports and Systematic Review of the Literature.儿童Grisel综合征:两例病例报告及文献系统综述
Case Rep Pediatr. 2020 Nov 12;2020:8819758. doi: 10.1155/2020/8819758. eCollection 2020.