Ferdinandov Dilyan, Yankov Dimo, Bussarsky Assen
Clinic of Neurosurgery, St. Ivan Rilski Hospital, Sofia, Bulgaria.
Surg Neurol Int. 2021 Jan 13;12:15. doi: 10.25259/SNI_733_2020. eCollection 2021.
The non traumatic, post inflammatory atlantoaxial rotatory instability, also known as Grisel's syndrome is a relatively rare condition usually affecting children. Adult cases are rare and even less frequently reported with separate case reports describing a single patient. Although antibiotic treatment and close neurological monitoring seem to be the gold standard of care, there is no general consensus on the optimal timing and extent of the surgical treatment.
We present a case of C1-C2 spondylitis, secondary to retropharyngeal abscess, without atlantoaxial instability on initial evaluation that progressed to C1-C2 subluxation with rapidly developing myelopathy 3 months after optimal antibiotic therapy and complete clinical and biochemical remission.
Grisel's syndrome is a rare condition in adults with secondary instability in spite of successful antibacterial treatment, which requires decompression and delayed surgical fixation in our case.
非创伤性、炎症后寰枢椎旋转性不稳,又称格里斯尔综合征,是一种相对罕见的疾病,通常影响儿童。成人病例罕见,单独病例报告描述单个患者的情况则更为少见。尽管抗生素治疗和密切的神经监测似乎是标准治疗方法,但对于手术治疗的最佳时机和范围尚无普遍共识。
我们报告一例继发于咽后脓肿的C1-C2脊柱炎病例,初始评估时无寰枢椎不稳,在最佳抗生素治疗及临床和生化指标完全缓解3个月后进展为C1-C2半脱位,并迅速出现脊髓病。
格里斯尔综合征在成人中罕见,尽管抗菌治疗成功仍会继发不稳,在我们的病例中需要减压和延迟手术固定。