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老年细胞学异常患者的部分气管切除术

Partial trachelectomy in the elderly patient with abnormal cytology.

作者信息

Krebs H B, Wilstrup M A, Wheelock J B

出版信息

Obstet Gynecol. 1985 Apr;65(4):579-84.

PMID:3982732
Abstract

Because of an unsatisfactory colposcopic examination, cold knife conization of the cervix is frequently required for the evaluation of postmenopausal patients with abnormal cervical cytology. With advancing age, the cervix atrophies and retracts so that conization becomes increasingly difficult and results in a tissue specimen that is frequently inadequate. Dissatisfied with the results of the standard conization procedure, the authors performed partial trachelectomy in 26 elderly patients with atrophic, retracted cervixes. The operative complications were acceptable. Twelve of the 26 patients (46%), including four with severe dysplasia and carcinoma in situ (CIS) and eight with invasive carcinoma, received additional therapy. Eleven of 14 patients (78%) with cervical intraepithelial neoplasia (CIN) had clear surgical margins; ten of these required no further therapy. The authors conclude that partial trachelectomy may be preferable to conization for the evaluation of elderly women with small, atrophic cervixes. It provides a specimen of sufficient length, so as to reduce the incidence of positive surgical margins and to decrease the need for additional therapy if no invasive neoplasia is found. The technique of partial trachelectomy is described.

摘要

由于阴道镜检查结果不理想,绝经后宫颈细胞学异常的患者常常需要进行宫颈冷刀锥切术来评估病情。随着年龄的增长,宫颈会萎缩并回缩,导致锥切术变得越来越困难,且获取的组织标本常常不充分。鉴于标准锥切术的结果不尽人意,作者对26例宫颈萎缩、回缩的老年患者实施了部分宫颈切除术。手术并发症在可接受范围内。26例患者中有12例(46%)接受了额外治疗,其中包括4例重度发育异常和原位癌(CIS)患者以及8例浸润癌患者。14例宫颈上皮内瘤变(CIN)患者中有11例(78%)手术切缘清晰;其中10例无需进一步治疗。作者得出结论,对于宫颈小且萎缩的老年女性,部分宫颈切除术可能比锥切术更可取。它能提供足够长度的标本,从而降低手术切缘阳性的发生率,并在未发现浸润性肿瘤时减少额外治疗的需求。文中还描述了部分宫颈切除术的技术。

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